This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes: polymerases, helicases and topoisomerases. The book aims not to beexhaustive, but rather to stimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.
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Langue Anglais ● Format PDF ● Pages 224 ● ISBN 9780192559968 ● Maison d’édition OUP Oxford ● Publié 2018 ● Téléchargeable 3 fois ● Devise EUR ● ID 8103278 ● Protection contre la copie Adobe DRM
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