Molecular Genetic Pathology presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Part I examines the clinical areas of molecular biology, genomics, pharmacogenomics and proteomics, while Part II covers the molecular areas of medical genetics, microbiology, hematology, transfusion medicine, oncology and forensic pathology. The volume provides a unique reference for the practicing pathologist and medical geneticist as well as a review book for residents and fellows in training in pathology, medical genetics and molecular genetic pathology.
Tabella dei contenuti
General Sections.- Principles of Clinical Molecular Biology.- Principles of Clinical Cytogenetics.- Diagnostic Methodology and Technology.- Tissue Microarrays and Biomarker Validation.- Laser Capture Microdissection.- Clinical Flow Cytometry.- Conceptual Evolution in Cancer Biology.- Clinical Genomics in Oncology.- Clinical Proteomics.- Clinical Pharmacogenomics.- Clonality Analysis in Modern Oncology and Surgical Pathology.- Fluorescence In Situ Hybridization (FISH) and Conventional Cytogenetics for Hematology and Oncology Diagnosis.- Instrumentation.- Genetic Inheritance and Population Genetics.- Genetic Counseling.- Disease-Based Sections.- Molecular Medical Genetics.- Prenatal Diagnosis.- Familial Cancer Syndromes.- Molecular Testing for Solid Tumors.- Molecular Pathology of the Central Nervous System.- Molecular Virology.- Molecular Bacteriology, Mycology, and Parasitology.- Molecular Testing for Coagulopathies.- Molecular Hemoglobinopathies.- Molecular Diagnostics of Lymphoid Malignancies.- Molecular Diagnostics of Myeloid Leukemias.- The HLA System and Transfusion Medicine.- Molecular Forensic Pathology.- Gene Therapy.- Ethical and Legal Issues in Molecular Testing.- Quality Assurance and Laboratory Inspection.
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