This book contains the refereed proceedings of the 16th International Conference on Business Information Systems, BIS 2013, held in Poznan, Poland, in June 2013. The theme of this year’s conference was "Business Applications on the Move, " reflecting the growing usage of mobile devices in business applications and its repercussions on business processes and information management.The 18 revised full papers were carefully reviewed and selected from 52 submissions. They are grouped into six sections on modern enterprises and mobile ERP, business models and BPM, linked data and ontologies, recommendations and content analysis, knowledge discovery, and IT frameworks and systems architecture.