A multidisciplinary approach to understanding the fundamentals of
mass spectrometry for bacterial analysis
From chemotaxonomy to characterization of targeted proteins,
Identification of Microorganisms by Mass Spectrometry provides an
overview of both well-established and cutting-edge mass
spectrometry techniques for identifying microorganisms. A vital
tool for microbiologists, health professionals, and analytical
chemists, the text is designed to help scientists select the most
effective techniques for use in biomedical, biochemical,
pharmaceutical, and bioterror defense applications.
Since microbiological applications of mass spectrometry require a
basic understanding of both microbiology and analytical chemistry,
the editors have incorporated material from both disciplines so
that readers from either field will come to understand the
necessary principles of the other. Featuring contributions from
some of the most recognized experts in both fields, this volume
provides specific examples of fundamental methods as well as
approaches developed in the last decade, including:
* Metastable atom bombardment pyrolysis mass spectrometry
* Matrix-assisted laser desorption/ionization mass spectrometry
(MALDI)
* MALDI time-of-flight mass spectrometry (MALDI-TOF MS) of intact
bacteria
* High-resolution Fourier transform mass spectrometry (FTMS)
* Electrospray ionization (ESI) mass spectrometry
Identification of Microorganisms by Mass Spectrometry represents
the most comprehensive and up-to-date work on the topic currently
available. It is liberally illustrated with figures and tables and
covers every aspect of spectrometric identification of
microorganisms, including experimental procedures, various means of
sample preparation, data analysis, and interpretation of complex
mass spectral data.
Yazar hakkında
CHARLES L. WILKINS, Ph D, is a Distinguished Professor in the
Department of Chemistry and Biochemistry at the University of
Arkansas. He is the author or coauthor of over 250 scientific
publications and has received numerous awards for his research.
JACKSON O. LAY, Jr., Ph D, is the Director of the Arkansas
Statewide Mass Spectrometry Facility at the University of Arkansas,
and the author or coauthor of more than 100 publications in the
field. In addition to his work with bacteria, he has developed mass
spectrometry methods for cancer research and toxicology.
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