This pocket reference guide is a must for all medical students and
junior doctors preparing for exams in pharmacology or needing a
rapid reminder during a clinical attachment.
In light of the growing pressures on those who prescribe drugs
to patients, increasing emphasis has been placed on the importance
of pharmacology in the undergraduate medical curriculum.
Rapid Clinical Pharmacology, with its concise,
easy-to-use approach, offers an appealing format for students to
use in both clinical practice and exam preparation and its
‘one-page per drug/class’ layout easily facilitates the
generation of a personal student formulary.
Each chapter of the book mirrors each section of the BNF to
allow easy cross-referencing and then each chapter is divided into
consistent sections as per other books in the Rapid series.
Rapid Clinical Pharmacology will also be available
as a mobile application for i Phone, i Pod Touch, i Pad and
Blackberry. See wiley.com/go/mededapps for further details.
Table of Content
Preface, ix
List of abbreviations, xi
Basic pharmacokinetic concepts
Gastrointestinal system
Histamine type 2 receptor antagonists, 5
Laxatives, 6
Proton pump inhibitors (PPIs), 7
Cardiovascular system
a-adrenoceptor antagonists (a blockers), 8
Adenosine, 9
Aldosterone antagonists, 10
Amiodarone, 11
Angiotensin-converting enzyme inhibitors (ACEIs), 12
Angiotensin II receptor blockers (ARBs), 13
Antimuscarinics, 14
Aspirin, 15
b-adrenoceptor antagonists (b blockers), 16
Calcium channel blockers (CCBs), 18
Cardiac glycosides, 19
Clopidogrel, 20
Dipyridamole, 21
Fibrates, 22
Fibrinolytics, 23
Flecainide, 24
Glycoprotein IIb/IIIa inhibitors, 25
Inotropic sympathomimetics, 26
Loop diuretics, 27
Low molecular weight heparins (LMWH), 28
Nitrates, 29
Potassium channel activators, 30
Statins, 31
Thiazide diuretics, 32
Tranexamic acid, 33
Vasoconstrictor sympathomimetics, 34
Warfarin, 35
Respiratory system
b2 adrenoceptor agonists, 36
Histamine type 1 receptor antagonists, 37
Inhaled antimuscarinics, 38
Leukotriene receptor antagonists, 39
Oxygen, 40
Theophylline, 41
Central nervous system
5-HT1 agonists (triptans), 42
5-HT3 antagonists, 43
Antihistamine anti-emetics, 44
Antipsychotics – atypical, 45
Antipsychotics – typical, 46
Benzodiazepines, 47
Carbamazepine, 48
Dopamine antagonist anti-emetics, 49
Drugs for dementia, 50
Gabapentin and pregabalin, 51
Levodopa (L-dopa), 52
Lithium, 53
Monoamine oxidase inhibitors (MAOIs), 54
Non-steroidal anti-inflammatory drugs (NSAIDs), 55
Opioid analgesia, 56
Other antiepileptics, 57
Other antiparkinsonian drugs, 58
Paracetamol, 59
Phenothiazine anti-emetics, 60
Phenytoin, 61
Selective serotonin reuptake inhibitors (SSRIs), 62
Sodium valproate, 63
Tricyclic antidepressants (TCAs), 64
Infections
Aciclovir, 65
Aminoglycosides, 66
Antifungals, 67
Antiretroviral agents, 68
Antituberculosis drugs, 69
Cephalosporins and other b lactams, 70
Penicillins, 71
Glycopeptide antibiotics, 72
Macrolides, 73
Metronidazole, 74
Nitrofurantoin, 75
Quinolones, 76
Tetracyclines, 77
Trimethoprim, 78
Endocrine system
5a-reductase inhibitors, 79
Antidiuretic hormone (ADH) analogues, 80
Biguanides, 81
Bisphosphonates, 82
Carbimazole, 83
Corticosteroids, 84
Dipeptidylpeptidase-4 (DDP-4) inhibitors, 85
Gonadotrophin-releasing hormone (Gn RH) agonists, 86
Hormone replacement therapy (HRT), 87
Incretin mimetics, 88
Insulins, 89
Levothyroxine, 90
Propylthiouracil, 91
Sulfonylureas, 92
Thiazolidinediones, 93
Obstetrics, gynaecology and urinary tract disorders
Contraceptives, 94
Mifepristone, 96
Oxybutynin, 97
Oxytocin, 98
Phosphodiesterase type 5 inhibitors, 99
Malignant disease and immunosuppression
Alkylating agents, 100
Anthracyclines, 101
Anti-androgens, 102
Antimetabolites, 103
Antiproliferative immunosuppressants, 104
Calcineurin inhibitors, 105
Other antineoplastic drugs, 106
Selective oestrogen receptor modulators (SERMs), 107
Trastuzumab (Herceptin), 108
Vinca alkaloids, 109
Musculoskeletal and joint diseases
Allopurinol, 110
Aminosalicylic acid compounds (ASAs), 111
Colchicine, 112
Methotrexate, 113
Contents vii
Eye
Antiglaucoma drugs, 114
Anaesthesia
Depolarising neuromuscular blocking agents, 115
Etomidate, 116
Inhalational anaesthetics, 117
Lidocaine, 118
Non-depolarising blocking agents, 119
Propofol, 120
Thiopental sodium, 121
Intravenous fluids
Blood and transfusion medicine
Index of drugs, 127
About the author
Andrew Batchelder is an Academic doctor at University Hospitals of Leicester (UHL).
Charlene Rodrigues is an Academic doctor at the London Deanery.
Ziad Alrifai is an Academic doctor at University Hospitals of Leicester (UHL).
Adrian Stanley is a Consultant Physician in Cardiovascular Medicine and Honorary Senior Lecturer (Medical Education), UHL.