Antoine Blancher & Jan Klein 
Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates [PDF ebook] 

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Zoologists have categorized primates into a single order, and no one doubts today that they share a common ancestry. Humans and Old and New World non- human primate species, from the lemurs of Madagascar to the African anthro- poid apes, represent diverging branches of an evolutionary common trunk. Along with species-specific characters, all primates have retained a number of ancestral traits, relics of their common origin. The comparative study of these species-specific and ancestral traits makes it possible to reconstruct the evolu- tionary pathways of humans and nonhuman primates. The discovery of the human blood groups and, later, of the Major Histocom- patibility Complex (MHC) had a seminal effect on the field of human genetics, providing the first sound examples of mendel ian polymorphisms. The use of blood group and MHC alleles as genetic markers in biological anthropology gen- erated a conceptual revolution and persuaded researchers to begin to think in terms of populations and not only intems of typology. The counterparts of these human red and white cell antigens were found and studied in nunhuman primates, and progress in this field is summarized in this book.

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Language English ● Format PDF ● ISBN 9783642590863 ● Editor Antoine Blancher & Jan Klein ● Publisher Springer Berlin Heidelberg ● Published 2012 ● Downloadable 3 times ● Currency EUR ● ID 6380219 ● Copy protection Adobe DRM
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