The Novartis Foundation is an international scientific and educational charity that promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
61 كتب إلكترونية بواسطة Derek J. Chadwick
Derek J. Chadwick & Jamie A. Goode: The hERG Cardiac Potassium Channel
This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of h ERG and the molecular basis for compound bin …
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€149.99
Derek J. Chadwick & Jamie A. Goode: Epithelial Anion Transport in Health and Disease
Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Mast Cells and Basophils
The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to stu …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Purinergic Signalling in Neuron-Glia Interactions
ATP, the intracellular energy source, is also an extremely important cell-cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry …
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€149.99
Derek J. Chadwick & Matthew Diamond: Percept, Decision, Action
Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception, comparing percepts to stored models (short-term …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Signalling Pathways in Acute Oxygen Sensing
Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are al …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Innate Immunity to Pulmonary Infection
Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infecti …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Molecular Clocks and Light Signalling
The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their abilit …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Nuclear Organization in Development and Disease
This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Vascular Development
The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration …
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€163.99
Derek J. Chadwick & Jamie A. Goode: Acetaldehyde-Related Pathology
Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived …
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€163.99
Derek J. Chadwick & David Evered: IgE, Mast Cells and the Allergic Response
Reviews recent basic research into Ig E, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses new methods of treatment. This symposium is uniqu …
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€121.99
Derek J. Chadwick & Gregory R. Bock: Human Genetic Information
As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields of molecular biology, medicine, philosophy, theolo …
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€121.99
Derek J. Chadwick & Kate Widdows: Steroids and Neuronal Activity
Classical studies of steroid hormones are concerned with their regulation of protein synthesis via the modulation of genomic transcription. But many of the actions of these hormones occur too rapidly …
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€121.99
Derek J. Chadwick & Joan Marsh: Bioactive Compounds from Plants
Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to environmental factors. The isolation and characteriza …
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€121.99
Derek J. Chadwick & Kate Widdows: Host-Guest Molecular Interactions
Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation of molecular assemblies containing two or more s …
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€121.99
Derek J. Chadwick & Joan Marsh: Catalytic Antibodies
Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antib …
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€121.99
Derek J. Chadwick & Kate Widdows: Protein Conformation
How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in the fields of NMR spectroscopy, X-ray crystallograp …
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€121.99
Derek J. Chadwick & Julie Whelan: Exploring Brain Functional Anatomy with Positron Tomography
Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET technology. Includes chapters on somatosensory, …
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€121.99
Derek J. Chadwick & Joan Marsh: Postimplantation Development in the Mouse
Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning stages of primitive streak formation. Discusses patt …
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€121.99
Derek J. Chadwick & Joan Marsh: Functional Anatomy of the Neuroendocrine Hypothalamus
Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into the function of the hypothalamus. …
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€121.99
Derek J. Chadwick & Julie Whelan: Aluminium in Biology and Medicine
Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known to damage animals and plants via acid rain. Examin …
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€121.99
Derek J. Chadwick & Julie Whelan: Secondary Metabolites
A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms. Examines the traditional context of secondary me …
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€121.99
Derek J. Chadwick & Joan Marsh: Corticotropin-Releasing Factor
Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide’s role in the control and coordination of the response to stress-inducing situa …
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€121.99
Derek J. Chadwick & Joan Marsh: Crop Protection and Sustainable Agriculture
The increase in the world population and changes in welfare have led to an enormously expanding demand for food. In the industrialized world, food surpluses rather than shortages are a problem togeth …
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€121.99
Derek J. Chadwick & Joan Marsh: The Molecular Basis of Smell and Taste Transduction
Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events in chemosensory transduction. In this book, the la …
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€121.99
Derek J. Chadwick & Kate Ackrill: The Biosynthesis of the Tetrapyrrole Pigments
Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the structure and regulation of key enzymes along w …
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€121.99
Derek J. Chadwick & Kate Ackrill: Circadian Clocks and Their Adjustment
Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control circadian rhythmicity and functioning in organisms …
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€121.99
Derek J. Chadwick & Joan Marsh: Ethnobotany and the Search for New Drugs
A compilation of articles by prominent experts in their respective fields on compensation for and collaboration with indigenous people in regard to their knowledge and provision of rare plants which …
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€121.99
Derek J. Chadwick & Joan Marsh: Vaccines Against Virally Induced Cancers
An interdisciplinary and multinational group of specialists present contributions describing the current status of vaccines against virally induced tumors and discuss the means by which they can be i …
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€121.99
Derek J. Chadwick & Gail Cardew: Somatostatin and Its Receptors
This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signal transduction; and the design and use of somatos …
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€121.99
Derek J. Chadwick & Jamie A. Goode: The Molecular Biology and Pathology of Elastic Tissues
Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics inclu …
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€121.99
Derek J. Chadwick & Gail Cardew: T Cell Subsets in Infectious and Autoimmune Diseases
T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents up-to-the-minute data on the role of T cells in au …
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€121.99
Derek J. Chadwick & Gail Cardew: Variation in the Human Genome
The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the momen …
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€121.99
Derek J. Chadwick & Jamie A. Goode: P2 Purinoceptors
Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions, behavioural disorders, inflammation, immunoregu …
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€121.99
Derek J. Chadwick & Gail Cardew: The Origins and Consequences of Obesity
This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international look at all aspects of the origins, consequences …
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€121.99
Derek J. Chadwick & Gail Cardew: Dental Enamel
The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuses on specific areas of research including the str …
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€121.99
Derek J. Chadwick & Gail Cardew: The Rising Trends in Asthma
Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising trend and includes research that has not yet been …
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€121.99
Derek J. Chadwick & Jamie A. Goode: Antibiotic Resistance
Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in an …
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€121.99
Derek J. Chadwick & Gail Cardew: Oligonucleotides as Therapeutic Agents
The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery of protein synthesis either by binding to the m …
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€121.99
Derek J. Chadwick & Gail Cardew: Telomeres and Telomerase
Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and functi …
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€114.99
Derek J. Chadwick & Gail Cardew: Epigenetics
Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized …
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€108.99
Derek J. Chadwick & Jamie A. Goode: Alcohol and Cardiovascular Disease
Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together much new and exciting work in this area, it reviews …
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€108.99
Derek J. Chadwick & Gail Cardew: Bacterial Responses to pH
Microbial responses to acidic and alkaline p H are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic p H are important in the understanding of the passage o …
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€108.99
Derek J. Chadwick & Jamie A. Goode: Insect-Plant Interactions and Induced Plant Defence
Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to defend themselves against attack by insects and pat …
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€163.99
Derek J. Chadwick & Gail Cardew: Gramicidin and Related Ion Channel-Forming Peptides
Gramicidin and Related Ion Channel-Forming Peptides Chair: Bonnie Wallace 1999 Gramicidin channels have been studied intensively for more than 25 years as model transport systems for large protein io …
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€108.99
Jamie A. Goode & Derek J. Chadwick: Rice Biotechnology
Rice is the most important food crop for half the world’s population. Over the last three decades, the imporvement in human nutrition and health in Asia has largely been attributable to a relatively …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Mitochondrial Biology
With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial re …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Growth Factors and Psychiatric Disorders
The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes wit …
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€163.99
Jamie A. Goode & Derek J. Chadwick: The Biology of Extracellular Molecular Chaperones
The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Role of the Sarcoplasmic Reticulum in Smooth Muscle
Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertens …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Cancer and Inflammation
Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and wound healing. The cells involved in inflammation are …
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€163.99
Derek J. Chadwick & Jamie A. Goode: Mucus Hypersecretion in Respiratory Disease
A number of chronic respiratory diseases including chronic bronchitis, asthma, cystic fibrosis and bronchiectasis are characterized by mucus hypersecretion. Following damage to the airway epithelium, …
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€149.99
Derek J. Chadwick & Jamie A. Goode: Mammalian TRP Channels as Molecular Targets
This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It covers the structure, function and regulation of ma …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Osteoarthritic Joint Pain
Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the qualit …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Development of the Cardiac Conduction System
The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias an …
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€149.99
Derek J. Chadwick & Jamie A. Goode: Pathological Pain
This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Mechanisms and Biological Significance of Pulsatile Hormone Secretion
This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage include …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Neuronal and Cognitive Effects of Oestrogens
Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Neural Transplantation in Neurodegenerative Disease
The field of neural transplantation is at a crucial stage in its development, with results of important clinical trials on transplantation in patients with Parkinson’s disease expected soon and novel …
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€161.99
