This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecie...
قائمة المحتويات
What is a quasispecies?- Historical origins and current scope.- The nucleation of semantic information in prebiotic matter.- Evolution of RNA-based networks.- Quas...
عن المؤلف
Esteban Domingo is a professor at the Spanish Research Council at Centro de Biología Molecular Severo Ochoa (Madrid) and President of the Spanish Society of Virology. He i...