The definitive guide to mass spectrometry techniques in biology
and biophysics
The use of mass spectrometry (MS) to study the architecture and
dynamics of proteins is increasingly common within the biophysical
community, and Mass Spectrometry in Structural Biology and
Biophysics: Architecture, Dynamics, and Interaction of
Biomolecules, Second Edition provides readers with detailed,
systematic coverage of the current state of the art.
Offering an unrivalled overview of modern MS-based armamentarium
that can be used to solve the most challenging problems in
biophysics, structural biology, and biopharmaceuticals, the book is
a practical guide to understanding the role of MS techniques in
biophysical research. Designed to meet the needs of both academic
and industrial researchers, it makes mass spectrometry accessible
to professionals in a range of fields, including
biopharmaceuticals.
This new edition has been significantly expanded and updated to
include the most recent experimental methodologies and techniques,
MS applications in biophysics and structural biology, methods for
studying higher order structure and dynamics of proteins, an
examination of other biopolymers and synthetic polymers, such as
nucleic acids and oligosaccharides, and much more.
Featuring high-quality illustrations that illuminate the
concepts described in the text, as well as extensive references
that enable the reader to pursue further study, Mass Spectrometry
in Structural Biology and Biophysics is an indispensable resource
for researchers and graduate students working in biophysics,
structural biology, protein chemistry, and related fields.
عن المؤلف
IGOR A. KALTASHOV, PHD, is a Professor in the Department of Chemistry at the University of Massachusetts Amherst.
STEPHEN J. EYLES, PHD, is a Senior Lecturer in the Department of Biochemistry and Molecular Biology, and the Director of the Mass Spectrometry Center at the University of Massachusetts Amherst.