An integrated and insightful look at successful drug synthesis in
today’s drug discovery market
The pharmaceutical industry is unquestionably vibrant today,
with drug synthesis making a vital contribution. Whether in the
early developmental stages of identifying and optimizing a lead, or
the latter stages of process development and cost-effective
scale-up, the ability to design elegant and economical synthetic
routes is often a major factor in the eventual viability and
c...
An integrated and insightful look at successful drug synthesis in
today’s drug discovery market
The pharmaceutical industry is unquestionably vibrant today,
with drug synthesis making a vital contribution. Whether in the
early developmental stages of identifying and optimizing a lead, or
the latter stages of process development and cost-effective
scale-up, the ability to design elegant and economical synthetic
routes is often a major factor in the eventual viability and
commercial success of a drug.
Contemporary Drug Synthesis examines how leading
researchers and manufacturers have integrated chemistry, biology,
pharmacokinetics, and a host of other disciplines in the creation
and development of leading drugs.
Authored by four of the pharmaceutical industry’s most respected
scientists, this timely volume:
* Focuses on the processes that resulted in high-profile drugs
including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and
over a dozen others
* Provides an in-depth introduction to each drug, followed by a
detailed account of its synthesis
* Organizes the drugs into fourteen therapeutic areas for clarity
and ease of use
Process chemists provide an essential bridge between chemistry and
the marketplace, creating scientifically practical drug processes
while never losing sight of the commercial viability of those
processes. Contemporary Drug Synthesis meets the needs of a
growing community of researchers in pharmaceutical research and
development, and is both a useful guide for practicing
pharmaceutical scientists and an excellent text for medicinal and
organic chemistry students.
