This book presents and discusses current research in the study of chemical modeling. Topics discussed include the periodic law and the Scerri’s periodic table; the family resemblance view of quantum mechanics; the relationship between electronic sharing in bonding and electronegtivity equalization of atoms in molecules; Gordy’ atomic electronegatiity ansatz; amphoteric, amphihydric and ambisaline; from cyclic silylenes to allenic strutures; and modeling and simulation of isothermal fixed-bed adsorption column.