For all of our advances in health care and achievements in public health that have contributed to an increased life expectancy, there still remain persistent problems in one’s community that are public health in origin. These persistent public health problems are well-studied from an academic standpoint, yet they evade a solution that is practical, economical, and socially just. These are complex, community-based, public health problems that disproportionally impact minority and immigrant populations. This book explores this topic in greater detail. Specifically, what have we, as public health academicians and practitioners learned when partnering with minority and immigrant community members to help them address persistent public health issues that affect them and their families on a daily basis? These are lessons that need to be shared so disadvantaged populations can build their capacity to address and solve persistent public health problems in their communities.