ERROR

Nous sommes désolés - même si nous avons fait de notre mieux: une erreur est survenue
Typedatabase
MessageYou have an error in your SQL syntax; check the manual that corresponds to your MariaDB server version for the right syntax to use near "AND SUBSTRING(categories_id,4,1) != "0") AS cat4, (SELECT categorie..." at line 5
QuerySELECT (SELECT categories_id FROM categories_description WHERE language_id = 4 AND categories_id = 000) AS cat1, (SELECT categories_id FROM categories_description WHERE language_id = 4 AND categories_id = 00 AND SUBSTRING(categories_id,2,1) != "0") AS cat2, (SELECT categories_id FROM categories_description WHERE language_id = 4 AND categories_id = 0 AND SUBSTRING(categories_id,3,1) != "0") AS cat3, (SELECT categories_id FROM categories_description WHERE language_id = 4 AND categories_id = AND SUBSTRING(categories_id,4,1) != "0") AS cat4, (SELECT categories_name FROM categories_description WHERE language_id = 4 AND categories_id = 000) AS cat1name, (SELECT categories_name FROM categories_description WHERE language_id = 4 AND categories_id = 00 AND SUBSTRING(categories_id,2,1) != "0") AS cat2name, (SELECT categories_name FROM categories_description WHERE language_id = 4 AND categories_id = 0 AND SUBSTRING(categories_id,3,1) != "0") AS cat3name, (SELECT categories_name FROM categories_description WHERE language_id = 4 AND categories_id = AND SUBSTRING(categories_id,4,1) != "0") AS cat4name, (SELECT url_text FROM commerce_seo_url_without_language WHERE categories_id = 000) AS cat1url, (SELECT url_text FROM commerce_seo_url_without_language WHERE categories_id = 00 AND SUBSTRING(categories_id,2,1) != "0") AS cat2url, (SELECT url_text FROM commerce_seo_url_without_language WHERE categories_id = 0 AND SUBSTRING(categories_id,3,1) != "0") AS cat3url, (SELECT url_text FROM commerce_seo_url_without_language WHERE categories_id = AND SUBSTRING(categories_id,4,1) != "0") AS cat4url, (SELECT wod_count_products FROM categories WHERE categories_id = 000) AS cat1cnt, (SELECT wod_count_products FROM categories WHERE categories_id = 00 AND SUBSTRING(categories_id,2,1) != "0") AS cat2cnt, (SELECT wod_count_products FROM categories WHERE categories_id = 0 AND SUBSTRING(categories_id,3,1) != "0") AS cat3cnt, (SELECT wod_count_products FROM categories WHERE categories_id = AND SUBSTRING(categories_id,4,1) != "0") AS cat4cnt

Shayne C. Gad & Charles B. Spainhour 
Nonclinical Drug Administration [PDF ebook] 
Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems

الدعم

If we will ever achieve Paul Ehrlich’s "magic bullet, " that is, a molecule which goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body, the practice of safety assessment will have to change. Nonclinical Drug Administration: Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems seeks to address a trio of objectives that, though separate, are linked and central to biomedical science and, ultimately, medicine. Rather seeing these as separate "silos, " those working in nonclinical safety assessment will have to view these three in an integrated manner and to regularly and thoughtfully incorporate new information and technology. The trio of objectives this book explores are: first, to present how to deliver more of a drug product systemically to facilitate the regulatory need for evaluating safety and efficacy in animal species (at elevated exposure levels) prior to advancing the drug to human testing; second is to achieve better tolerance to therapeutics administration in test animals and humans which achieves objectives 1 and 3; and third, to explore ways to improve on therapeutic target receptor delivery performance, therefore improving both clinical pharmacodynamics bioavailability and specificity. The book’s ten chapters assemble the basic concepts, principles and hypotheses involved in quantitative receptor and chronological organism interaction dynamics central to the successful development of new therapeutics which depend on systemic administration to achieve desired therapeutic goals and in so doing avoid outcomes which limit, marginalize, or preclude the therapeutic use of so many molecules.

€224.07
طرق الدفع
قم بشراء هذا الكتاب الإلكتروني واحصل على كتاب آخر مجانًا!
لغة الإنجليزية ● شكل PDF ● صفحات 420 ● ISBN 9781466502598 ● الناشر CRC Press ● نشرت 2017 ● للتحميل 3 مرات ● دقة EUR ● هوية شخصية 5355164 ● حماية النسخ Adobe DRM
يتطلب قارئ الكتاب الاليكتروني قادرة DRM

المزيد من الكتب الإلكترونية من نفس المؤلف (المؤلفين) / محرر

33٬253 كتب إلكترونية في هذه الفئة