Board on Health Sciences Policy & Forum on Neuroscience and Nervous System Disorders 
Sex Differences in Brain Disorders [EPUB ebook] 
Emerging Transcriptomic Evidence: Proceedings of a Workshop

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Cover of Board on Health Sciences Policy & Forum on Neuroscience and Nervous System Disorders: Sex Differences in Brain Disorders (ePUB)

Accumulating evidence gathered over the past three decades has demonstrated a biological basis for differences between men and women with respect to clinical features and treatment responses to several neuropsychiatric, neurodevelopmental, and neurodegenerative disorders. Dramatic sex differences have also been identified in the brain transcriptomes of individuals with multiple brain disorders, including depression, posttraumatic stress disorder, and autism. The brain transcriptome includes all of the messenger RNA as well as the non-protein-coding RNA molecules expressed in brain tissue and thus represents gene activity. To explore these sex-based transcriptomic differences further, the National Academies of Sciences, Engineering, and Medicine’s Forum on Neuroscience and Nervous System Disorders hosted a workshop on September 23, 2020, titled Sex Differences in Brain Disorders: Emerging Transcriptomic Evidence and Implications for Therapeutic Development. The workshop brought together a broad spectrum of stakeholders to share cutting-edge emerging evidence, discuss challenges, and identify future opportunities and potential directions. This publication summarizes the presentation and discussion of the workshop.

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Language English ● Format EPUB ● Pages 62 ● ISBN 9780309265232 ● Editor Clare Stroud & Lisa Bain ● Publisher National Academies Press ● Published 2021 ● Downloadable 3 times ● Currency EUR ● ID 7973867 ● Copy protection Adobe DRM
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