This book provides state of the art information on the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic neuromuscular disorders. The opening section discusses the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, with special focus on the role of electromyography and antibody testing. Each of the relevant clinical entities is then discussed in detail, the coverage including, for example, myasthenia gravis, polymyositis, immune-mediated neuropathies, multifocal motor neuropathies, amyotrophic lateral sclerosis, paraneoplastic neuropathies, and diabetic polyneuropathy. Clear guidance is provided on currently available treatments, with descriptions of the latest advances in physiotherapy, drug therapy, and respiratory care. Other features of this clinically oriented book are the inclusion of many illustrative case presentations and contributions by international authors from leading centers.
Table of Content
Foreword.- Introduction.- Part I Diagnosis of acquired myopathies.- Auto-Antibodies in Neuromuscular Disorders.- Electromyography.- Imaging of the Muscle.- Peripheral Nerve Ultrasound.- Magnetic Resonance Imaging of the Peripheral Nerve.- Part II Clinical Entities.- The Spectrum of Inflammatory Myopathies: Dermatomyositis, Polymyositis, Necrotizing Myositis and Inclusion Body Myositis.- Necrotising Myopathy.- Statin Myopathy.- Myasthenia Gravis.- Acquired Autoimmune Rippling Muscles with Myasthenia Gravis.- Endocrinological Myopathies.- Vitamin D deficiency in Muscle.- Intensive Care Unit Acquired Weakness.- Part III Neurogenic disorders.- Idiopathic Chronic Immune-Mediated Neuropathies: Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy.- GBS Immune Neuropathies.- Amyotrophic Lateral Sclerosis – Epidemiology and Risk Factors.- Paraneoplastic Diseases of the Peripheral Nervous System.- Diabetic Neuropathy.- Infectious Neuropathies.-Toxic Neuropathies.
About the author
Corrado Angelini is Professor of Neurology and Director of the Neuromuscular Center at the University of Padua, Italy, a position he has held since 1980. Since 2010 he has also been a Consultant at IRCCS Fondazione San Camillo Hospital in Venice. After completing his MD at the University of Padua and specializing in Neurology, Dr. Angelini studied and worked for more than 4 years in the United States (in Minnesota, North Dakota, Colorado, and California) before returning to Italy to take up his position at the University of Padua. Dr. Angelini is an Associate Member of the American Academy of Neurology and has been Chair of the ENS Muscle and Neuromuscular Junction Committee since 2009. He has received several honors during his career and is the author of numerous articles in international peer-reviewed journals. Dr. Angelini is a member of the advisory board of Neurology and Neurological Sciences and a Springer author.
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