Presents state-of-the-art applications in hyaluronan research, from hyaluronan’s physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan’s synthesis and catabolism, its role in cells, its interactions with specific binding proteins, and its role in the embryonic nervous system.
Table of Content
Partial table of contents:
Secondary Structures in Hyaluronan Solutions: Chemical and
Biological Implications (J. Scott).
Turnover and Metabolism of Hyaluronan (J. Fraser & T.
Laurent).
Enzymic Pathways of Hyaluronan Catabolism (L. Rodén,
et al.).
Hyaluronan and Hyaluronan-Binding Proteins in Cartilaginous
Tissues (R. Mason, et al.).
The Role of a Cell-Associated Hyaluronan-Binding Protein in
Fibroblast Behavior (E. Turley).
The Role and Regulation of Tumor-Associated Hyaluronan (W.
Knudson, et al.).
Interactions Between Cells of the Immune System and Hyaluronate
Synthesis by Human Dermal Fibroblasts (T. Whiteside & R.
Buckingham).
Hyaluronan and Angiogenesis (D. West & S. Kumar).
Changes in Hyaluronan Concentration in Tissues and Body Fluids
in Disease States (A. Engström-Laurent).
The Specific Interaction Between Fibrin(ogen) and Hyaluronan:
Possible Consequences in Hemostasis, Inflammation and Wound Healing
(P. Weigel, et al.).
General Discussion.
Index of Contributors.
Subject Index.
About the author
David Evered and Julie Whelan are the editors of The Biology of Hyaluronan and other titles.
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