This book contains the refereed proceedings of two long-running events held along with the CAi SE conference relating to the areas of enterprise, business-process and information systems modeling:* the 23rd International Conference on Business Process Modeling, Development and Support, BPMDS 2022, and * the 27th International Conference on Exploring Modeling Methods for Systems Analysis and Development, EMMSAD 2022.The conferences were taking place in Leuven, Belgium during June 6-7, 2022. For BPMDS 7 full papers and 2 short papers were carefully reviewed and selected for publication from a total of 18 submissions; for EMMSAD 11 full papers and 3 short papers were accepted from 30 submissions after thorough reviews.The papers were organized in topical sections as follows:BPMDS: Actual and perceived challenges; business process modeling; understanding collaboration: one issue, many perspectives; and event logs why it derivates;EMMSAD: Foundations of modeling and method engineering; enterprise, business process, and capability modeling; information systems and requirements modeling; domain-specific and knowledge modeling; and evaluation of modeling approaches.