This scholarly introductory treatment explores the fundamentals of modern geostatistics, viewing them as the product of the advancement of the epistemic status of stochastic data analysis. The book’s main focus is the Bayesian maximum entropy approach for studying spatiotemporal distributions of natural variables, an approach that offers readers a deeper understanding of the role of geostatistics in improved mathematical models of scientific mapping. Starting with a overview of the uses of spatiotemporal mapping in the natural sciences, the text explores spatiotemporal geometry, the epistemic paradigm, the mathematical formulation of the Bayesian maximum entropy method, and analytical expressions of the posterior operator. Additional topics include uncertainty assessment, single- and multi-point analytical formulations, and popular methods. An innovative contribution to the field of space and time analysis, this volume offers many potential applications in epidemiology, geography, biology, and other fields.