This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their molecular pathogenesis, clinicopathological features, classification, molecular diagnosis, and approaches to personalized care.
Written by experts in the field,
Precision Molecular Pathology of Neoplastic Pediatric Diseases serves as a valuable resource for pathologists, pediatric oncologists, trainees and researchers with an interest in pediatric and molecular pathology.
Inhaltsverzeichnis
Principles of Molecular Biology.- Molecular Oncogenesis.- Molecular Testing in Oncology.- Molecular Methods in Oncology: Targeted Mutational Analysis.- Molecular Methods in Oncology: Genomic Analysis.- Molecular Targeted Therapy of Pediatric Neoplasms.- Hematolymphoid System.- Nervous System.- Neuroblastoma and neuroblastic tumors.- Skin, Soft Tissue and Bone.- Head and Neck.- Cardiovascular and Respiratory System.- Gastrointestinal Tract.- Liver and Pancreas.- Genitourinary.
Über den Autor
Larissa V. Furtado, MD
Medical Director, Molecular Oncology
ARUP Laboratories
Assistant Professor of Pathology
University of Utah School of Medicine
500 Chipeta Way
MS J15-113
Salt Lake City, Utah, 84108
Aliya N. Husain, MD
Professor of Pathology
University of Chicago Medicine
5841 S. Maryland Ave., Room S-627, MC 6101
Chicago, IL 60637
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