Providing a comprehensive insight into cellular signaling processes in bacteria with a special focus on biotechnological implications, this is the first book to cover intercellular as well as intracellular signaling and its relevance for biofilm formation, host pathogen interactions, symbiotic relationships, and photo- and chemotaxis. In addition, it deals in detail with principal bacterial signaling mechanisms — making this a valuable resource for all advanced students in microbiology. Dr. Krämer is a world-renowned expert in intracellular signaling and its implications for biotechnology processes, while Dr. Jung is an expert on intercellular signaling and its relevance for biomedicine and agriculture.
Inhaltsverzeichnis
INTERCELLULAR COMMUNICATION
Intercellular Communication: Introduction
Cell-cell Communication and Biofilm Formation in Gram-positive Bacteria
Cell-cell Communication in Biofilms of Gram-negative Bacteria
Cell Interactions Guide the Swarming and Fruiting Body Development of Myxobacteria
Communication between Rhizobia and Plants
Communication between Pathogens and Eukaryotic Cells
Identification of Bacterial Autoinducers (Methods Chapter)
TRANSMEMBRANE SIGNALING
Transmembrane Signaling: Introduction
Outer Membrane Signaling in Gram-negative Bacteria
Stimulus Perception and Signaling by Histidine Kinases
Chemotaxis and Receptor Localization
Photoreception and Signal Transduction
Transmembrane Signaling
Sensory Transport Proteins
Regulated Intramembrane Proteolysis in Bacterial Transmembrane Signaling
Protein Chemical and EPR Spectroscopic Approaches to Monitor Membrane Protein Structure and Dynamics (Methods Chapter)
INTRACELLULAR SIGNALING
Intracellular Signaling: Introduction
Protein Domains Involved in Intracellular Signal Transduction
Sensing of Oxygen by Bacteria
Microbial Sensor Systems for Dihydrogen, Nitric Oxide, and Carbon-monoxide
Signal Transduction by Trigger Enzymes: Bifunctional Enzymes and Transporters Controlling Gene Expression
Regulation of Carbohydrate Utilization by Phosphotransferase System-Mediated Protein Phosphorylation
Cyclic AMP Signaling in Prokaryotes
Cyclic-di-GMP Signaling
pp Gpp Signaling
Sensory RNAs
Signal Transduction by Serine/Threonine Protein Kinases in Bacteria
Regulated Proteolysis and Signal Transduction in Bacteria
Intracellular Signaling and Gene Target Analysis (Methods Chapter)
Über den Autor
Reinhard Krämer is chair in Biochemistry at Cologne University, Germany. After studying Biochemistry at the Universities of Tübingen and Munich, he obtained his Ph.D. from LMU Munich. He then spent 10 years at the Research Center Jülich (Institute of Biotechnology) and the University of Düsseldorf as an Associate Professor for Biochemistry before taking up his present position at Cologne University. During his scientific career, R. Krämer has focused on different aspects of membrane transport proteins, both in mitochondria and in prokaryotes, as well as on stress response in bacteria, in particular osmotic stress.
Kirsten Jung studied biochemistry and performed her doctoral thesis at the University of Leipzig in 1988. After postdoctoral studies at the Howard Hughes Medical Institute, University of California, Los Angeles, she continued her research at the University of Osnabrück. In 2002 she was appointed as Associate Professor for Microbiology at the Technical University of Darmstadt, and in 2004 she became Full Professor and Chair for Microbiology at the Ludwig-Maximilians-Universität Munich. Research of Kirsten Jung is focused on the molecular mechanisms of stimulus perception by sensor kinases involved in environmental stress response.