Se-Kwon Kim 
Marine Microbiology [PDF ebook] 
Bioactive Compounds and Biotechnological Applications

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Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues.

Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.

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Inhaltsverzeichnis

PREFACE

INTRODUCTION TO MARINE ACTINOBACTERIA
Introduction
Actinobacteria
Origin and Distribution of Marine Actinobacteria
Isolation and Identification of Marine Actinobacteria
Indigenous Marine Actinobacteria
Role of Actinobacteria in the Marine Environment
Importance of Marine Actinobacteria
Symbioses
Bioinformatics
Conclusions

TREASURE HUNTING FOR USEFUL MICROORGANISMS IN THE MARINE ENVIRONMENT
Introduction
Microorganisms Living in the Marine Environment
Microorganisms Living in Deep Sea Water

STRATEGY OF MARINE VIRUSES IN GLOBAL ECOSYSTEM
Introduction
Reproductive Strategies of Viruses
Abundance of Marine Viruses
Viral Activities in Ecosystems
Recent Advancement of Viruses versus Diseases
The Effect of Ocean Acidification on Marine Viruses
Further Aspects

TAXONOMIC STUDY OF ANTIBIOTIC-PRODUCING MARINE ACTINOBACTERIA
Introduction
Materials and Methods
Result
Discussion
Conclusion

MARINE CYANOBACTERIA: A PROLIFIC SOURCE OF BIOACTIVE NATURAL PRODUCTS AS DRUG LEADS
Introduction
Bioactive Secondary Metabolites from Marine Cyanobacteria
Conclusions

MARINE BACTERIA ARE AN ATTRACTIVE SOURCE TO OVERCOME THE PROBLEMS OF ANTIBIOTIC-RESISTANT STAPHYLOCOCCUS AUREUS
Introduction
Strategies for Overcoming Antibiotic Resistance of Bacteria
Marine Bacteria Are Attractive Natural Sources for Overcoming Antibiotic Resistance of MRSA

MARINE BACTERIA AS PROBIOTICS AND THEIR APPLICATIONS IN AQUACULTURE
Introduction
Definition of Probiotics in Aquaculture
Selecting and Developing Probiotics in Aquaculture
Effects of Probiotics on Aquatic Organisms
Probiotics in the Larviculture 1
Problems Associated with Probiotics Development
Further Work and Conclusions

SMALL-MOLECULE ANTIBIOTICS FROM MARINE BACTERIA AND STRATEGIES TO PREVENT REDISCOVERY OF KNOWN COMPOUNDS
Antibiotic Activity of Marine Bacteria
Structurally Elucidated Marine Bacterial Antibiotics
Cosmopolitan Antibiotics: the Rediscovery Problem
Future Strategies for the Discovery of Marine Bacterial Antibiotics
Conclusions and Perspectives

MARINE BACTERIOPHAGES FOR THE BIOCONTROL OF FISH AND SHELLFISH DISEASES
Introduction
Mode of Action of Phages
Diversity of Marine Phages
Application of Marine Phages to Control Fish and Shellfish Diseases
Potentials and Limitations of Phage Therapy in Marine Fish and Shellfish

MARINE ACTINOMYCETES AS SOURCE OF PHARMACEUTICALLY IMPORTANT COMPOUNDS
Introduction
Marine Actinomycetes as Source of Therapeutics
Marine Actinomycete Compounds as Antibacterials
Marine Actinomycete Compounds as Antitumors/Antiproliferative
Marine Actinomycete Enzymes as Antiproliferatives
Marine Actinomycete Compounds as Antimalarials
Marine Actinomycete Compounds as Antifungals
Bioactive Compounds from Sponge-Associated Actinomycetes
Conclusion

ANTIMICROBIAL AGENTS FROM MARINE CYANOBACTERIA AND ACTINOMYCETES
Introduction
Antimicrobials from Marine Actinomycetes
Antimicrobials from Marine Cyanobacteria
Current Research Status: Challenges and Future Prospects
Conclusions

BIOACTIVE COMPOUNDS FROM MARINE ACTINOMYCETES
Introduction
Actinomycetes
Diversity and Distribution of Marine Actinobacteria
Bioactive Compounds
Conclusions

FUNGAL BIOACTIVE GENE CLUSTERS: A MOLECULAR INSIGHT
Introduction to Fungal Secondary Metabolites
Polyketide Synthase
Nonribosomal Peptide Synthetase
PKS and NRPS Products
Conclusions

ANTICANCER POTENTIALS OF MARINE-DERIVED FUNGAL METABOLITES
Introduction
Marine Fungi
Cancer: Initiation, Progression, and Therapeutics
Anticancer Metabolites of Marine Fungal Origin
Future Prospects and Concluding Remarks

ANTIFUNGAL AND ANTIMYCOTOXIN ACTIVITIES OF MARINE ACTINOMYCETES AND THEIR COMPOUNDS
Introduction
Diversity of Actinomycetes in the Sea
Diversity of Natural Compounds from Marine Actinomycetes
Biological Activities
Conclusions

ANTITUBERCULOSIS MATERIALS FROM MARINE MICROBES
Introduction
Marine Microbe-Derived Antituberculosis Agents
Conclusions

HARNESSING THE CHEMICAL

Über den Autor

Professor Se-Kwon Kim, Ph D, currently serves as a senior professor in the Department of Chemistry and the director of the Marine Bioprocess Research Center (MBPRC) at Pukyong National University in the Republic of Korea. He received his BSc, MSc, and Ph D from the Pukyong National University and joined as a faculty member. He has previously served as a scientist in the University of Illinois, Urbana
Champaign, Illinois (1988 – 1989), and was a visiting scientist at the Memorial University of Newfoundland in Canada (1999 – 2000).

Professor Se-Kwon Kim was president of the Korean Society of Chitin and Chitosan (1986 – 1990) and the Korean Society of Marine Biotechnology (2006 – 2007). He was also the chairman for the 7th Asia-Pacific Chitin and Chitosan Symposium, which was held in South Korea in 2006. He is one of the board members of the International Society of Marine Biotechnology and the International Society for Nutraceuticals and Functional Foods. Moreover, he was the editor in chief of the Korean Journal of Life Sciences (1995 – 1997), the Korean Journal of Fisheries Science and Technology (2006 – 2007), and the Korean Journal of Marine Bioscience and Biotechnology (2006 – present). His research has been credited with the best paper award from the American Oil Chemist’s Society (AOCS) and the Korean Society of Fisheries Science and Technology in 2002.

Professor Se-Kwon Kim’s major research interests are investigation and development of bioactive substances derived from marine organisms and their application in oriental medicine, nutraceuticals, and cosmeceuticals via marine bioprocessing and mass- production technologies. He has also conducted research on the development of bioactive materials from marine organisms for applications in oriental medicine, cosmeceuticals, and nutraceuticals. To date, he has authored over 500 research papers and holds 110 patents. In addition, he has written or edited more than 40 books.
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Sprache Englisch ● Format PDF ● Seiten 580 ● ISBN 9783527665280 ● Dateigröße 19.6 MB ● Herausgeber Se-Kwon Kim ● Verlag Wiley-VCH ● Erscheinungsjahr 2013 ● Ausgabe 1 ● herunterladbar 24 Monate ● Währung EUR ● ID 2761685 ● Kopierschutz Adobe DRM
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