A unique, holistic approach covering all functions and phases of
pharmaceutical research and development
While there are a number of texts dedicated to individual aspects
of pharmaceutical research and development, this unique contributed
work takes a holistic and integrative approach to the use of
computers in all phases of drug discovery, development, and
marketing. It explains how applications are used at various stages,
including bioinformatics, data mining, predicting human response to
drugs, and high-throughput screening. By providing a comprehensive
view, the book offers readers a unique framework and systems
perspective from which they can devise strategies to thoroughly
exploit the use of computers in their organizations during all
phases of the discovery and development process.
Chapters are organized into the following sections:
* Computers in pharmaceutical research and development: a general
overview
* Understanding diseases: mining complex systems for
knowledge
* Scientific information handling and enhancing productivity
* Computers in drug discovery
* Computers in preclinical development
* Computers in development decision making, economics, and market
analysis
* Computers in clinical development
* Future applications and future development
Each chapter is written by one or more leading experts in the field
and carefully edited to ensure a consistent structure and approach
throughout the book. Figures are used extensively to illustrate
complex concepts and multifaceted processes. References are
provided in each chapter to enable readers to continue
investigating a particular topic in depth. Finally, tables of
software resources are provided in many of the chapters.
This is essential reading for IT professionals and scientists in
the pharmaceutical industry as well as researchers involved in
informatics and ADMET, drug discovery, and technology development.
The book’s cross-functional, all-phases approach provides a unique
opportunity for a holistic analysis and assessment of computer
applications in pharmaceutics.
Über den Autor
SEAN EKINS, PHD, DSC, is an Adjunct Associate Professor in the Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy. Dr. Ekins is the author of more than seventy peer-reviewed papers and book chapters as well as several patents. He serves on editorial boards for the Journal of Pharmacological and Toxicological Methods, Drug Metabolism and Disposition, Drug Discovery Today, and Pharmaceutical Research.
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