Reviews recent basic research into Ig E, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses new methods of treatment. This symposium is unique in the Ig E field for its breadth of coverage and interdisciplinary nature, and it shows the benefits from the current rapid expansion of knowledge in cell biology, immunology, and molecular genetics, as well as the potential clinical significance of this research to clinical immunologists and allergologists.
Table of Content
Partial table of contents:
Control of in Vivo Ig E Production in the Mouse by
Interleukin 4 (F. Finkelman, et al.).
Different Mast Cell Mediators Produced by Different Mast Cell
Phenotypes (M. Gurish & K. Austen).
Mast Cells: Immunologically Specific Effectors and Potential
Sources of Multiple Cytokines During Ig E-Dependent Responses (S.
Galli, et al.).
The Receptor with High Affinity for Ig E (H. Metzger, et
al.).
Calcium: An Important Second Messenger in Mast Cells (C.
Fewtrell, et al.).
Low Affinity Ig E Receptors: Regulation and Functional Roles in
Cell Activation (J. Yodoi, et al.).
Ig E and Inflammatory Cells (A. Capron, et al.).
Molecular Genetics of Human Responsiveness to Allergens (D.
Marsh, et al.).
Influence of Environmental Factors on Ig E Production (S.
Takafuji, et al.).
Epidemiology of the Allergic Response (K. Turner).
Conventional and New Approaches to Hyposensitization (A. de
Weck).
Index of Contributors.
Subject Index.
About the author
Derek J. Chadwick and David Evered are editors for Ig E, Mast Cells and the Allergic Response and other scientific titles.
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