Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics include the structure, ultrastructure and function of elastin; elastin regulation; elastin’s role in aging, lung development and disease and atherosclerosis; as well as related aspects of pharmacology and nutrition.
Table of Content
Partial table of contents:
Molecular Biophysics of Elastin Structure, Function and
Pathology (D. Urry, et al.).
Ultrastructure of Elastin (I. Pasquali-Ronchetti, et
al.).
GENERAL DISCUSSION I: HYDROXYLATION OF THE PENTAPEPTIDE VGVPG IN
OVINE ELASTIN.
Structure of the Elastin Gene (J. Rosenbloom, et
al.).
Catalytic Properties and Structural Components of Lysyl Oxidase
(H. Kagan, et al.).
GENERAL DISCUSSION II: EVOLUTIONARY ASPECTS.
The Structure and Function of Fibrillin (D. Reinhardt, et
al.).
Elastin Gene Mutations in Transgenic Mice (J. Sechler, et
al.).
GENERAL DISCUSSION III: Elastin in Lung Development and Disease
(R. Pierce, et al.).
Elastin in Systemic and Pulmonary Hypertension (F. Keeley &
L. Bartoszewicz).
GENERAL DICUSSION IV: DEVELOPMENTAL REGULATION OF ELASTIN
PRODUCTION.
Elastin in Blood Vessels (L. Robert, et al.).
GENERAL DISCUSSION V: THE NON-ENZYMIC GLYCATION OF ELASTIN.
Interaction of Tumour Cells with Elastin and the Metastatic
Phenotype (J. Tímár, et al.).
A Role for Neutrophil Elastase in Solar Elastosis (B. Starcher
& M. Conrad).
Indexes.
About the author
Derek J. Chadwick and Jamie A. Goode are editors for The Molecular Biology and Pathology of Elastic Tissues and other scientific titles.
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