Telomerase is a ribonucleoprotein enzyme that catalyzes the cellular synthesis of telomeric DNA during cellular division, resulting in maintenance of telomere length and increased proliferative potential.Several studies suggest that the telomerase may play an important role in the diagnosis and prognosis of cancer because its expression strongly correlates with the potential tumor progression. Ninety percent of human cancers on different organs have shown high telomerasa activity. This book reviews research in the field of telomerase including functions of telomerase independent of its interaction with telomeres on gene expression and chromatin structure; histone deacetylase inhibition as an anticancer telomerase-targeting strategy and others.
Aiden N. Gagnon
Telomerase [PDF ebook]
Composition, Functions and Clinical Implications
Telomerase [PDF ebook]
Composition, Functions and Clinical Implications
¡Compre este libro electrónico y obtenga 1 más GRATIS!
Formato PDF ● Páginas 171 ● ISBN 9781617283390 ● Editor Aiden N. Gagnon ● Editorial Nova Science Publishers ● Publicado 2016 ● Descargable 3 veces ● Divisa EUR ● ID 7219733 ● Protección de copia Adobe DRM
Requiere lector de ebook con capacidad DRM