The later stages of dementia are as important, if not more so, as
the earlier stages, since they harbour unique characteristics and
events, which profoundly affect the lives of patients and their
carers. Severe dementia has not had a high profile in the
clinical literature as until recently prognosis was poor and there
were few beneficial interventions. With the recent licensing of
memantine, clinicians finally have a drug option that will delay
disease progression.
Severe Dementia is the first book to focus
exclusively on severe dementia. It addresses both the clinical
features of the disease and the social aspects of care.
Introductory chapters on the differential diagnosis, neurochemistry
and molecular pathology of severe dementia set the scene for the
clinical discussion. Detailed clinical chapters on cognitive
function, depression, physical effects, staging and function
follow. All therapeutic interventions are then discussed,
including memantine, anticholinesterases, neuroleptics and
non-pharmacological treatment. The final chapters review the social
and economic aspects of dementia care, including family
involvement, person-centered care, palliative care, ethics and
health economics.
Written and edited by experts in geriatric psychiatry and
geriatrics, Severe Dementia is of value to all
clinicians involved in the management of this complex and
vulnerable group of patients. It is also of interest to
general practitioners and carers in nursing homes.
Tabla de materias
List of contributors.
Introduction.
PART 1: INTRODUCTORY.
Chapter 1: Assessment and Diagnosis of Severe Dementia (Paul
Newhouse and Joseph Lasek).
Chapter 2: Neurochemistry of Severe Dementia (Sally I. Sharp,
Paul T. Francis and Clive G. Ballard).
Chapter 3: The Molecular Pathology of Severe Dementia (Clive
Holmes).
PART 2: CLINICAL FEATURES OF SEVERE DEMENTIA.
Chapter 4: Cognitive Functions in Severe Dementia (Judith
Saxton and François Boller).
Chapter 5: Behavioural and Psychological Symptons of Dementia
– Agitation (E. Jane Byrne and Deborah Collins).
Chapter 6: Depression in Severe Dementia (Kate Bielinski and
Brian Lawlor).
Chapter 7: Physical Aspects of Severe Alzheimer’s Disease
(Bruno Vellas).
Chapter 8: Clinical Features of Severe Dementia: Staging
(Barry Reisberg, Jerzy Wegiel, Emile Franssen, Sridhar Kadiyala,
Stefanie Auer, Liduïn Souren, Marwan Sabbagh and James
Golomb).
Chapter 9: Clinical Features of Severe Dementia: Function
(Serge Gauthier).
PART 3: MANAGEMENT.
Chapter 10: Drug Treatment: Memantine (Anton P. Porsteinsson
and Pierre N. Tariot).
Chapter 11: Drug Treatment: Cholinesterase Inhibitors
(Michael Woodward and Howard Feldman).
Chapter 12: Drug Treatment: Treatment of Behavioural and
Psychological Symptoms of Dementia with Neuroleptics (Peter Paul
De Deyn).
Chapter 13: Non-pharmacological Treatment of Severe Dementia: An
Overview (Ross Overshott and Alistair Burns).
Chapter 14: Non-pharmacological Treatment of Severe Dementia:
the Seattle Protocols (Rebecca G. Logsdon, Linda Teri and Sue M.
Mc Curry).
Chapter 15: Care by Families for Late Stage Dementia (Steven
H. Zarit and Joseph E. Gaugler).
Chapter 16: Person-centred Care for People with Severe Dementia
(Murna Downs, Neil Small and Katherine Froggatt).
Chapter 17: Palliative Care in Patients with Severe Dementia
(Raymond Koopmans, H. Roeline W. Pasman and Jenny T. van
der Steen).
Chapter 18: Narrative Ethics and Ethical Narratives in Dementia
(Clive Baldwin).
Chapter 19: Health Economics of Severe Dementia (Anders Wimo
and Bengt Winblad).
Index.
Sobre el autor
Professor Alistair Burns, University of Manchester, UK,
Professor of Old Age Psychiatry, Director of Research and
Development for the South Manchester University Hospitals’ Trust,
Editor of the International Journal of Geriatric Psychiatry, Chair
of the UK Alzheimer’s Society Medical and Scientific Advisory
Committee Panel, Immediate past-president of the International
Psychogeriatrics Association (IPA)
Dr. Bengt Winblad, Karolinska Institute, Stockholm,
Sweden, Professor of Geriatric Medicine, IPA Board Member, member
of the Nobel Assembly for the Prize of Medicine and Physiology at
the Karolinska Institute, Research Director of the Stockholm
Gerontology Research Center.
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