An overview of biomedical applications and the toxicity properties of carbon nanomaterials aimed at helping to avoid detrimental health effects while laying the groundwork for further research in this highly relevant field.
Summarizing recent research, the book starts with the synthesis and functionalization of carbon nanomaterials, as well as identification and detection in biosystems. It then moves on to the interaction between carbon nanoparticles and biocomponents, focusing on the toxicity and mechanisms to various organs and systems and potential biomedical applications as well. Each section highlights the challenges, outlines unanswered questions, and suggests directions for further research and development efforts.
Tabla de materias
Synthesis, Functionalization and Characterization
Identification and Detection in Biological Systems
In-vivo Biodistribution and Pharmacokinetics of Carbon Nanomaterials
Biomedical Applications of Carbon Nanomaterials
Interaction of Carbon Nanomaterials and Components in Biological Systems
Pulmonary Effects
Cardiovascular and Hemostatic Effects
Modulation to Immune System
Toxicity to Liver and Kidneys
Potential Toxicity to Nervous System
Genotoxicity and Carcinogenesis Potential
Effect on Reproduction and Development
Effect on GIT and Skin
Molecular Mechanism of Toxicity
Exposure Scenarios in Working Place and Risk Assessment of Nanomaterials
Transport in Environment and Ecotoxicity
Sobre el autor
Chunying Chen is principal investigator in the Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety at the National Center for Nanoscience and Technology of China. She obtained her Ph D degree in biomedical engineering from Huazhong University of Science and Technology of China. Chunying Chen has authored and co-authored more than 150 peer-reviewed papers, 3 books and 6 book chapters, has 12 issued patents and one international standard. She has been awarded the National Award for Innovation and Outstanding Service to the Standard authorized by Standardization Administration of the People’s Republic of China in 2011, the Second Prize of Beijing Science and Technology in 2008, the Second Prize of the National Natural Science Award in 2012, the National Science Fund for Distinguished Young Scholars, and China Outstanding Young Female Scientists Awards in 2014.
Haifang Wang is professor in the Institute of Nanochemistry and Nanobiology at the Shanghai University. She received her BSc and MSc degrees in chemistry from Fudan University and Ph D degree in chemistry from Peking University. From 1994 to 2008, she was a faculty at Peking University. As a visiting scholar, she spent one year at the Institute of Physical and Chemical Research (RIKEN), Japan and one year at Clemson University, USA. In 2009, she moved to Shanghai University. She is the editorial board member of Nanomedicine (Lond.) and the standing committee member of Nanotoxicology Committee, Chinese Society of Toxicology. She has published over 120 scientific papers and book chapters, and was awarded the Second Prize of the National Natural Science Award in 2012 (third place).