Asthma is one of the most important diseases affecting our society.
It is an extremely common condition that reduces quality of life,
and acute exacerbations can be life-threatening. It affects a
disproportionate number of children. With the overwhelming volume
of research being carried out in this field specialists need a
method of keeping up-to-date with current opinion.
As with the other ‘Challenges’ books, ‘Challenges in Asthma’ is
aimed at hospital specialists and therefore assumes a certain level
of knowledge about the disease. It builds on this by discussing
only areas of controversy and uncertainty in both the basic
understanding of asthma and its management. An international author
list will provide stimulating debate with, and ultimately draw some
conclusions from, existing data which will benefit readers in their
day-to-day practice.
Tabla de materias
List of contributors.
Preface.
Acknowledgements..
PART 1: Epidemiology.
1. Why is the incidence of asthma increasing (P.M. Matricardi
and S. Bonini).
2. Why is asthma more common in the West (E. Von Mutius).
3. How much asthma can be attributed to atopic sensitization (R.
Beasley, J. Douwes, J. Pekkanen and N.E. Pearce).
4. Is air pollution important in asthma (A.J.
Chauhan).
PART 2: Pathophysiology.
5. Is infection important in the pathogenesis and clinical
expression of asthma (E.R. Sutherland and R.J. Martin).
6. Does infection in early life protect against or cause asthma
(B. Bjorksten).
7. Does asthma progress to chronic obstructive pulmonary disease
(S.T. Weiss).
8. Antenatal factors in the development of atopy and asthma
(P.G. Woodruff, S.L. Prescott, P.G. Holt and J.V. Fahy).
9. Genetics of asthma: What’s new (I. Sayers, B. Beghe, J.
Holloway and S.T. Holgate).
PART 3: Treatment.
10. Can airway fibrosis be prevented (D. Smallwood and J.
Wilson).
11. Does allergen avoidance help? What are the practical
measures that patients can take (A. Custovic and A. Woodcock).
12. Is early treatment of children necessary (P.J. Helms).
13. What are the mechanisms of corticosteroid resistance in
asthma (P.J. Barnes).
14. What new therapies are being developed for asthma and will
they offer something better than steroids (J.C. Kips, K.G. Tournoy
and R.A. Pauwels).
15. What is the orel of long-acting ß2 -agonists in the
treatment of asthma (M.R. Sears).
16. What is the role of leukotriene modifiers in the treatment
of asthma (M.E. Wechsler and J.M. Drazen).
PART 4: Delivery of Care.
17. What are the issues in delivering care in primary care (D.
Price).
18. Are asthma clinics useful: should they be run by the doctors
or the nurse (B.D.W. Harrison and S.M. Mildenhall).
19. Should asthma be managed by the patient or the doctor: is
education important (M.R. Partridge).
20. Are psychosocial factors important in asthma (B.D.W.
Harrison and S.M. Mildenhall).
Index.
Sobre el autor
Sebastian L. Johnston and Stephen T. Holgate are the authors of Asthma: Critical Debates, published by Wiley.
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