Donald L. Trump & Candace S. Johnson 
Vitamin D and Cancer [PDF ebook] 

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Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to be involved in immune function, cardiovascular health, thrombosis and vasculogenesis and neuromuscular function. Considerable epidemiologic data demonstrate that low vitamin D serum levels occur very commonly in normal adult populations and that vitamin D deficiency is associated with an enhanced risk of cancer death from lung, prostate, head & neck, colorectal and other gastrointestinal cancers. In addition, preclinical data provide evidence that calcitriol and other active analogues of calcitriol have anti-proliferative, pro-differentiative, pro-apoptotic and anti-angiogenic activity in numerous in-vitro and in-vivo models. It is quite clear that, while it requires high exposure to calcitriol to induce these effects, such exposure can be readily achieved when high dose intermittent therapy is given.

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Langue Anglais ● Format PDF ● Pages 342 ● ISBN 9781441971883 ● Taille du fichier 5.5 MB ● Âge 02-99 ans ● Éditeur Donald L. Trump & Candace S. Johnson ● Maison d’édition Springer New York ● Lieu NY ● Pays US ● Publié 2010 ● Téléchargeable 24 mois ● Devise EUR ● ID 2150386 ● Protection contre la copie DRM sociale

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