In recent years, there have been significant developments in detector technologies in the field of astrophysics, requiring lower temperatures with simple self-contained refrigerators. Temperatures in the range of 1K to 50m K are now achieved by using dedicated closed-cycle miniature sorption coolers.This book presents the theoretical and experimental knowledge necessary to design and build your own miniature refrigerators, including both single shot and continuous 1 K, 300 m K and 100 m K coolers, and details how to write the needed design software. This text will be of interest to students and researchers, already familiar with basic physics and thermodynamics, who want to understand how sorption coolers and miniature dilution refrigerators work. Features: The first book dedicated to miniature sorption coolers Covers the basic thermodynamic concepts needed to understand the behavior of liquid helium-3 and liquid helium-4 Includes an appendix of Python example codes