This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
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Langue Anglais ● Format PDF ● Pages 242 ● ISBN 9781000714548 ● Maison d’édition CRC Press ● Publié 2020 ● Téléchargeable 3 fois ● Devise EUR ● ID 8112562 ● Protection contre la copie Adobe DRM
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