This new edition overviews drug transporters and presents the
principles of drug transport and associated techniques, featuring
new chapters on multidrug and toxin extrusion proteins, placental
transport, in silico approaches in drug discovery, and
regulatory guidance for drug transport studies in drug
development.
* Describes drug transporter families, mechanisms,
and clinical implications along with experimental methods for
studying and characterizing drug transporters
* Includes new chapters on multidrug and toxin extrusion
proteins, placental transport and in silico approaches in drug
discovery
* Has a new chapter covering regulatory guidance for the
evaluation of drug transport in drug development with global
criteria used for drug transporters in clinical trials
* Arranges material to go from fundamental mechanisms to
clinical outcomes, making the book useful for novice and expert
readers
A propos de l’auteur
Guofeng You is a Distinguished Professor of Pharmaceutics
in the Ernest Mario School of Pharmacy at Rutgers University, USA.
She has published numerous original research articles in the field
of drug transport. She has been serving on several grant review
panels of the National Institutes of Health and is on the editorial
boards of leading journals. She was the coeditor for the first
edition of this book (Wiley, 2007).
Marilyn E. Morris is Professor in the Department of
Pharmaceutical Sciences at the University at Buffalo, State
University of New York. She is a Fellow of the American Association
of Pharmaceutical Scientists (AAPS) and the American Association
for the Advancement of Science (AAAS). and currently serves on the
editorial boards of leading journals and was also co-editor for the
first edition of this book (Wiley, 2007).
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