This volume collects fifteen original essays on E. J. Lowe’s work on metaphysics and ontology. The essays connect Lowe’s insights with contemporary issues in metaphysics.E. J. Lowe (1950-2014) was one of the most influential analytical philosophers of the twentieth and early twenty-first century. Drawing inspiration from Aristotle’s thought, E. J. Lowe treated metaphysics as an autonomous discipline concerned with the fundamental structure of reality. The chapters in this volume reflect on his path-breaking work. They deal with a wide range of metaphysical issues including four-category ontology, the causal and non-causal aspects of agency, categorial fundamentality and non-fundamentality, the existence of relations, property dualism, powers and abilities, personal identity, predication, and topological ontology. Taken together, the chapters reflect the liveliness of contemporary debates in metaphysics and the enduring impact of Lowe’s thought on them.E. J. Lowe and Ontology will be of interest to researchers and advanced students working in metaphysics and philosophy of mind.