This volume explores the nexus of manifestations of hematopathology and dermatopathology and provides a novel compartmental(epidermal, dermal, subcutaneous) -based framework to approach a diagnosis that considers both pseudolymphomatous and lymphomatous patterns. Through photographs, tables, and text, the book illustrates the range of non-neoplastic hematologic disorders and their neoplastic counterparts in skin: reactive patterns of infectious etiology and immune responses that simulate cutaneous lymphomas. The epidemiology, pathobiology, clinical and immuno-histopathologic manifestations in skin as well as the approach to diagnosis, selection and algorithmic interpretation of tests, and prognosis are also described.
Written by experts in the field, Cutaneous Hematopathology: Approach to the Diagnosis of Atypical Lymphoid-Hematopoietic Infiltrates in Skin is a comprehensive resource that is of great value to surgical pathologists, hematopathologists, dermatopathologists, residents and fellows, community dermatologists, oncologists and infectious disease practitioners.
Table of Content
Patterns of Lymphohistiocytic Reaction in Skin: An Approach to Cutaneous Lymphohematopoieitic Infiltrate Using Histologic Patterns and Immunostains.- Functional Organization of the Skin as an Immune Response Organ: Skin, Immune Response and Useful Immunohistochemistry.- Role of Immunohistochemistry and Chromogenic In Situ Hybridization in Diagnosis.- Role Of Molecular Genetic and Flow Cytometry Analysis In Cutaneous Hematopathology- Including Application in Ten Disease Categories: Using Molecular and Immunophenotyping Technics in Evaluation of Hyperplasia, Atypical Infiltrates, and Frank Lymphomas.- Epidermotropic Reactions.- Neoplastic Epidermotropic Diseases.- Nodular B Lymphocyte Reactive Patterns: Reactive Nodular B-cell Pattern.- T-cell Pseudolymphoma Presenting in a Lichenoid and Nodular Pattern.- Neoplastic Nodular B-Cell Pattern.- Neoplastic Nodular T Cell Pattern: An Approach to Diagnosis of Neoplastic Nodular T-cell Lymphomas of Skin.- Subcutaneous Pattern: Subcutaneous Lymphoproliferative Disorders.- CD30+ Cutaneous Lymphoproliferative Disorders and Pseudolymphomas.- Lymphohistiocytic and Granulomatous Dermatitis: Differential Diagnosis of Granulomatous Dermatitis.- Cutaneous Pathology of Emergent and Tropical Infections: Skin, Infectious Pathogens, Emergent and Tropical Infections.- Cutaneous Lymphoid Infiltrates in Patients Receiving Biologic Modifiers.- Cutaneous Myelomonocytic Infiltrates.- Cutaneous Intravascular Conditions.- Non-Lymphoid Tumors Mimicking Lymphoma.
About the author
Hernani D. Cualing, MD IHCFLOW Diagnostic Laboratory, Department of Hematopathology and Cutaneous Lymphoma, Lutz, FL, USA
Marshall E. Kadin, MDBoston University School of Medicine, Roger Williams Medical Center, Department of Dermatology, Providence, RI, USA
Mai P. Hoang, MDHarvard Medical School, Massachusetts General Hospital, Department of Pathology, Boston, MA, USA
Michael B. Morgan, MDUniversity of South Florida College of Medicine, Pensacola and Atlanta Dermpath Diagnostics, Tampa, FL, USA
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