Author: Herwald

Bartonella henselae is a bacterial pathogen that has been observed in sections of clinical specimen from patients with cat scratch disease. The first cultivation of this organism was successful in th …

Aspergillus fumigatus has become one of the most important fungal human pathogens in industrialized countries. It causes different diseases like allergic bronchopulmonary aspergillosis, aspergilloma, …

Varicella-zoster virus (VZV), a member of the herpesvirus family, is known as the causative agent of chickenpox (varicella) and shingles (zoster). In the past decades, considerable knowledge about th …

For a long time, parvoviruses were mostly known in the field of veterinary medicine. Interest in these viruses broadened, however, after it was shown that one member can be harmful to humans and that …

The importance of yeast pathogens causing life-threatening systemic and tenacious superficial infections in humans has been steadily increasing over the last few decades. Species of the genus Candida …

Cryptosporidia and microsporidia are protozoan parasites that have emerged as human pathogens over the last two decades. With the coming of AIDS they have been recognised as important opportunistic p …

One of the greatest public health achievements during the last century was the reduction of infectious diseases due to public sanitation measures, vaccines and antibiotics. However, in recent years, …

Animal testing has a long history, and the resulting knowledge has brought about a significant contribution to the improvement of health and welfare of mankind and animals. Federal regulations concer …

The last decade of intensive research in the field of infectious diseases has resulted in a better conceptual understanding of the molecular mechanisms behind the host-parasite interactions that lead …

This second, completely revised and extended edition of Prions: A Challenge for Science, Medicine and the Public Health System is a comprehensive, up-to-date review of prions and prion-associated dis …

Over the past few decades the increase in bacterial resistance has led to the search for novel antibacterial therapies and a better understanding of virulence mechanisms used by pathogens. It has bee …

The last two decades have shown that the local microenvironment plays a pivotal role in cancer progression. Cancer is not the result of mutation events in single cells, but of a complex interplay of …

This volume provides an overview of exacerbation models of asthma and chronic obstructive pulmonary disease (COPD). Within this wide field the book focuses on experimental systems that mimic pathobio …

The last decade has witnessed the delineation of innate immunity – a new area which has revolutionized our understanding of host-parasite interactions and their impact on defense mechanisms in infect …

Over the last fifteen years it has become increasingly obvious that bacteria are not as simple and solitary as once believed. Rather, an accumulating body of work shows that bacteria are highly compl …

Sepsis is a serious condition that is associated with high mortality despite advanced modern medical treatment. Recent years have witnessed novel paradigms describing host responses in sepsis. In par …