Patrick M. Woster, Ph.D. is Professor and Center for Economic Excellence Endowed Chair in the Department of Pharmaceutical and Biomedical Sciences at the Medical University of South Carolina. He is a medicinal chemist with an interest in the synthesis of molecules that modulate polyamine metabolism or chromatin remodeling as potential antitumor agents. Dr. Woster also maintains a program in antiparasitic drug discovery with a particular emphasis on malaria and trypanosomiasis. He has produced a number of inhibitors that target enzymes in the polyamine biosynthetic pathway, and synthesized the first unsymmetrically substituted alkylpolyamine analogues. Molecules developed in the Woster laboratory have been shown to produce dramatic effects on a variety of tumor cells by initiating apoptosis, binding to DNA and by producing epigenetic changes in gene expression. Robert A. Casero, Jr., Ph.D. is a Professor of Oncology in the Johns Hopkins University School of Medicine. Dr. Casero is a molecular pharmacologist who has spent most of the last 30 years studying the role of polyamines in normal and tumour cell growth, and devising strategies to target polyamine function and metabolism for therapeutic benefit. His laboratory was responsible for cloning several genes involved in human polyamine catabolism; genes whose expression are thought to play a role in determining cellular responses to specific polyamine analogues.
10 द्वारा ईबुक Andrew Goodwin
Andrew Goodwin & Garry Whannel: Understanding Television
Understanding Television offers an introduction to some of the issues of television broadcasting and its main genres. It examines a number of programme categories, such as news, drama-documentary, si …
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Simon Frith & Andrew Goodwin: On Record
Classic sociological analyses of ‘deviance’ and rebellion; studies of technology; subcultural and feminist readings, semiotic and musicological essays and close readings of stars, bands and the fans …
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Simon Frith & Andrew Goodwin: Sound and Vision
Sound and Vision is the first significant collection of new and classic texts on video and brings together some of the leading international cultural and music critics writing today. Addressing one o …
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€25.69
Simon Frith & Andrew Goodwin: Sound and Vision
Sound and Vision is the first significant collection of new and classic texts on video and brings together some of the leading international cultural and music critics writing today. Addressing one o …
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€46.18
Simon Frith & Andrew Goodwin: Sound and Vision
Sound and Vision is the first significant collection of new and classic texts on video and brings together some of the leading international cultural and music critics writing today. Addressing one o …
PDF
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€46.21
Simon Frith & Andrew Goodwin: On Record
Classic sociological analyses of ‘deviance’ and rebellion; studies of technology; subcultural and feminist readings, semiotic and musicological essays and close readings of stars, bands and the fans …
EPUB
अंग्रेज़ी
DRM
€46.40
Simon Frith & Andrew Goodwin: On Record
Classic sociological analyses of ‘deviance’ and rebellion; studies of technology; subcultural and feminist readings, semiotic and musicological essays and close readings of stars, bands and the fans …
PDF
अंग्रेज़ी
DRM
€46.40
Andrew Goodwin & Garry Whannel: Understanding Television
Understanding Television offers an introduction to some of the issues of television broadcasting and its main genres. It examines a number of programme categories, such as news, drama-documentary, si …
EPUB
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DRM
€46.05
Andrew Goodwin & Garry Whannel: Understanding Television
Understanding Television offers an introduction to some of the issues of television broadcasting and its main genres. It examines a number of programme categories, such as news, drama-documentary, si …
PDF
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€46.21
Patrick Woster & Robert Casero: Polyamine Drug Discovery
Polyamines are ubiquitous molecules that are involved in a number of important cellular processes. Aberrations in their function or metabolism play a role in diseases such as cancer and parasitic inf …
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€179.99