Despite his skill as a world-class transplant surgeon, Dr. Aaron Berk is powerless to save his dying wife, Alexie. Her rare blood type makes it doubtful she will get a heart transplant in time to save her life. An accident victim arrives at his hospital and Berk learns she has Alexie’s same blood type. If Lily Carr becomes brain-dead, he can keep her alive on machines until her healthy heart can be harvested for his beloved wife. When Dr. Jordan Bradshaw, director of a federal grant at the same hospital, uncovers disturbing information about Lily’s past, he has to consider that his transplant research might present an ugly reality. His life unravels with alarming speed as he seeks the help of his best friend, Detective Dan Yazzie to search for answers and, more importantly, to stay alive.