The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume.The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures.The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.
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भाषा अंग्रेज़ी ● स्वरूप PDF ● पेज 374 ● ISBN 9780309584906 ● प्रकाशक National Academies Press ● प्रकाशित 1993 ● डाउनलोड करने योग्य 3 बार ● मुद्रा EUR ● आईडी 7147468 ● कॉपी सुरक्षा Adobe DRM
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