The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. Variation in the Human Genome discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the evolution and migration of human populations. Specific disorders such as cystic fibrosis, beta-thalassaemia, fragile X, phenylketonuria and tumour development susceptibility are used to illustrate this genetic variability and mechanisms of gene mutation and evolution.
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विषयसूची
Partial table of contents:Phyogeographic Variability in Traditional Societies (R. Ward
& D. Valencia).
Interpreting Genetic Variability: The Effects of Shared
Evolutionary History (P. Donnelly).
Microsatellites: Evolution and Mutational Processes (N. Freimer
& M. Slatkin).
Genetic and Geographical Variability on Cystic Fibrosis:
Evolutionary Considerations (J. Bertranpetit & F.
Calafell).
Population Genetics of Tumours (W. Bodmer & I.
Tomlinson).
World Distribution of HLA Alleles and Implications for Disease
(J. Bodmer).
The Genetics of Common Diseses: The Implications of Population
Variability (D. Weatherall).
Final Discussion.
Summary.
Indexes.
लेखक के बारे में
Derek J. Chadwick and Gail Cardew are editors for Variation in the Human Genome and other scientific titles.यह ईबुक खरीदें और 1 और मुफ़्त पाएं!
भाषा अंग्रेज़ी ● स्वरूप PDF ● पेज 340 ● ISBN 9780470514894 ● फाइल का आकार 18.9 MB ● संपादक Derek J. Chadwick & Gail Cardew ● प्रकाशक John Wiley & Sons ● प्रकाशित 2008 ● डाउनलोड करने योग्य 24 महीने ● मुद्रा EUR ● आईडी 2318984 ● कॉपी सुरक्षा Adobe DRM
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