One of few books to cover all aspects of cyclin-dependent kinases (CDKs), this volume examines CDKs as molecular and functional entities, their role in various disease processes, and their potential for pharmacological modulation. The book first explains the integration of cell cycle control pathways, opportunities for targeting, targets of inhibitors, and the evaluation of CDK inhibitors. Then it examines the design, development, and chemistry of small molecule CDK inhibitors. The final section assesses the current status of CDK inhibitors in clinical trials, the therapeutic deployment challenges of small molecule inhibitors, and the future prospects of CDK inhibitors as anticancer agents.
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स्वरूप PDF ● पेज 448 ● ISBN 9781420005400 ● संपादक Paul J. (Cardiff University, Wales, UK) Smith & Eddy W. (Incyte Corporation, Wilmington, Delaware, USA) Yue ● प्रकाशक CRC Press ● प्रकाशित 2006 ● डाउनलोड करने योग्य 3 बार ● मुद्रा EUR ● आईडी 5696479 ● कॉपी सुरक्षा Adobe DRM
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