Molecular Analysis and Genome Discovery, Second Edition is a completely revised and updated new edition of this successful book. The text provides a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical information on current techniques currently being researched and developed. Each chapter offers an up-to-date analysis of the subject encompassing the very latest technology platforms and is an essential reference for researchers in the field looking for an up-to-date overview of the subject. The book will also be an indispensable resource for those working in the biotechnology and pharmaceutical industries. New for this edition: chapters on Genotyping through Mutation Detection; Differential Gene Expression; Haplotyping and Molecular Profiling.
विषयसूची
Overview of Genotyping
Mònica Bayés and Ivo Glynne Gut
Centro Nacional de Análisis Genómico
C/Baldiri Reixac 4, 08028 Barcelona, Spain
DNA Chip Analysis in Genome Discovery
Ross N. Nazar and Jane Robb
Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada N1G 2W1
q PCR, theory, reliability & use in molecular analysis
Jamie Murphy & Stephen A Bustin
Academic Surgical Unit, 3rd Floor Alexandra Wing,
Royal London Hospital, Whitechapel, London E1 1BB.
DNA Analysis in Droplet-Based Microfluidic Devices
Pinar Ozdemir, Yonghao Zhang
Department of Mechanical Engineering, University of Strathclyde, Glasgow, G1 1XJ, UK
High Resolution Melt Profiling
*Steven F. Dobrowolski Ph D and Carl T. Wittwer MD, Ph D
Department of Pathology
University of Utah
School of Medicine
Massively Parallel Sequencing
Tracy Tucker1, Marco Marra1, 2, Jan M Friedman1, 3
Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, V6H 3N1 Canada;
BC Cancer Agency Genome Sciences Centre, Vancouver, British Columbia, V5Z 4S6 Canada;
Child & Family Research Institute, Vancouver, British Columbia, V6H 3N1 Canada;
Aptamers for Analysis: nucleic acids ligands in the post genomic era
Pedro Nadali, Alessandro Pintoi, Marketa Svobodovai and Ciara K. O’ Sullivan*, i, ii
i Department d’Enginyeria Quimica, Universitat Rovira i Virgili, Avinguda Països Catalans 26, 43007 Tarragona, Spain.
ii Institució Catalana de Recerca i Estudis Avançats, Passeig Lluís Companys, 23, 08010 Barcelona, Spain
Use of Nanotechnology for Enhancing of Cancer Biomarker Discovery and Analysis: A Molecular Approach
Farid E. Ahmed, Ph.D.
GEM Tox Consultants & Labs, Inc., Greenville, NC 27834, USA
Chip Based Proteomics
Julian Bailes, Andrew Milnthorpe, Sandra Smieszek, Mikhail Soloviev
School of Biological Sciences, Royal Holloway, University of London, Egham, , Surrey, TW20 0EX, UK
Antibody Microarrays in Proteome Profiling
Mohamed Saiel Saeed Alhamdani and Jörg D. Hoheisel
Division of Functional Genome Analysis, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
Mass Spectrometry and Metabolomics
William J. Griffiths and Yuqin Wang
Institute of Mass Spectrometry, School of Medicine, Room 352 Grove Building, Swansea University, Singleton Park, Swansea SA2 8PP, Wales, UK.
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