The focus of this book is on the design of a specific control strategy using digital computers. This control strategy referred to as Sliding Mode Control (SMC), has its roots in (continuous-time) relay control. This book aims to explain recent investigations’ output in the field of discrete-time sliding mode control (DSMC). The book starts by explaining a new robust LMI-based (state-feedback and observer-based output-feedback) DSMC including a new scheme for sparsely distributed control. It includes a novel event-driven control mechanism, called actuator-based event-driven scheme, using a synchronized-rate biofeedback system for heart rate regulation during cycle-ergometer.Key Features: Focuses on LMI-based SMC (sliding mode control) for uncertain discrete-time system using novel nonlinear components in the control law Makes reader understand the techniques of designing a discrete controller based on the flexible sliding functions Proposes new algorithms for sparsifying control and observer network through multi-objective optimization frameworks Discusses a framework for the design of SMC for two-dimensional systems along with analyzing the controllability of two-dimensional systems Discusses novel schemes for sparsifying the control network