This comprehensive, yet practical, text is a ready collection of the most up-to-date information on primary CNS tumors. Authored by a carefully selected group of the world’s leading clinicians and scientists, the book is divided into three sections. The opening chapters cover general principles, including epidemiology, pathogenesis, tumor stem cells, supportive care, complications of therapy, and quality of life. The remaining two sections are comprised of treatment-oriented chapters covering the spectrum of gliomas and rarer tumor types. Each of these chapters presents multi-disciplinary therapeutic approaches and addresses specific disease concerns. Throughout, the authors incorporate the cutting-edge advances in molecular biology and genomics that are revolutionizing neuro-oncology. The result is an important clinical resource which provides evidence-based data and interpretation essential to intelligent therapeutic decision making.
Tabella dei contenuti
Part I: General Principles.- 1 – Epidemiology and Risk Factors.- 2 – Molecular Pathogenesis.- 3 – Brain Tumor Stem Cells.- 4 – Principles of Supportive Care.- 5 – Principles of Clinical Trial Design and Response Assessment.- 6 – Complications of Therapy.- 7 – Neuropsychological Function and Quality of Life.- Part II: Gliomas.- 8 – Low-Grade Gliomas.- 9 – High-Grade Astrocytomas.- 10 – Anaplastic Oligodendrogliomas and Mixed Gliomas.- 11 – Ependymomas.- 12 – Uncommon Gliomas in Adults: Brainstem Gliomas, Pilocytic Astrocytomas and Pleomorphic Xanthoastrocytomas.- Part III: Other Tumor Types.- 13 – Pediatric Tumors.- 14 – Primary Central Nervous System Lymphoma.- 15 – Meningiomas.- 16 – Pituitary Adenomas.- 17 – Vestibular Schwannomas.- 18 – Medulloblastomas.- 19 – Pineal Region Tumors.- 20 – Genetic Syndromes.- 21 – Rare Tumors.- 22 – Spinal Tumors.
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