This book deals with the formulation of industrial products Its field of application goes from food-processing industry to the industry of elastomers showing that the principles of development follow always the same methodology.
Tabella dei contenuti
Preface xi
PART ONE: GENERAL INFORMATION 1
Chapter 1. Introduction 3
André CHEYMOL
1.1. Definition 3
1.2. Historical background 3
1.3. From art to science 8
1.4. Overview of the economical impact of the aforementionedproducts 14
1.5. Book presentation and structure 15
1.6. Bibliography 16
Chapter 2. Formulation in Major Organic Chemistry Industries19
André CHEYMOL
2.1. Necessity and concept 19
2.2. Factors affecting different industries 26
2.3. Outlining a methodology 27
2.4. Bibliography 30
PART TWO: CONCEPT AND APPLICATION 31
Chapter 3. Solutions 33
Anne-Marie PENSÉ-LHÉRITIER
3.1. Introduction 33
3.2. Solubilizing in water 35
3.3. Solubilizing in solvents 37
3.4. Processes to help solubilization 43
3.5. Conclusion 48
3.6. Bibliography 49
Chapter 4. Dispersions 53
Gérard HOLTZINGER
4.1. Introduction 53
4.2. Particles and their specificities 54
4.3. Various particle systems and stability issues 62
4.4. Dispersion methods and analysis techniques 89
4.5. Rheology 107
4.6. Bibliography 115
Chapter 5. Formulation of Emulsions 119
Anne-Marie PENSÉ-LHÉRITIER
5.1. General aspects of emulsions 119
5.2. Theoretical considerations on the liquid-liquidinteractions 121
5.3. Developing the emulsion 125
5.4. Stabilizing an emulsion 134
5.5. Formulation of emulsions 141
5.6. Conclusion 144
5.7. Bibliography 144
Chapter 6. Suspensions 147
Gérard HOLTZINGER
6.1. Dispersion theory 148
6.2. Formulation of suspensions 155
6.3. Stability agents of suspensions 158
6.4. Specific case of the pharmaceutical realization 164
6.5. Specific case of cosmetics 164
6.6. Using dispersion 167
6.7. Bibliography 183
Chapter 7. Dispersions in High-Viscosity Mediums: Formulating Polymers 185
André CHEYMOL
7.1. Characterization of polymers 185
7.2. Formulation of polymers: general information 198
7.3. Thermal behavior 211
7.4. Heat generation and transmission 216
7.5. Main mixing tools 218
7.6. Conclusion on the polymer formulation rules 227
7.7. Bibliography 227
PART THREE: FORMULATION OF MAJOR PRODUCTS 231
Chapter 8. Dosage Form and Pharmaceutical Development233
Vincent FAIVRE
8.1. Drugs development 233
8.2. Case study: development of a dosage form for oraladministration 246
8.3. Monitoring/checking methods 249
8.4. Bibliography 252
Chapter 9. Formulation of Cosmetic Products 253
Caroline ROUSSEAU
9.1. Introduction 253
9.2. Specifications 254
9.3. Development in the laboratory 256
9.4. Industrial fabrication 265
9.5. Product launch 265
9.6. Regulations 266
9.7. Conclusion 267
Chapter 10. Formulation of Food Products 269
Christine CHÊNÉ
10.1. Specifications 269
10.2. Constraints 271
10.3. Formulation methodology 279
Chapter 11. Formulation of Elastomers 283
André CHEYMOL
11.1. Introduction 283
11.2. Choice of the elastomers 284
11.3. Adjuvants required to obtain crucial functions 290
11.4. Formulation realization: mixture 312
11.5. Conclusion 317
11.6. Bibliography 318
Conclusion 321
List of Authors 323
Index 325
Circa l’autore
Anne-Marie Pensé-Lhéritier is the author of Formulation, published by Wiley.
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