Mifepristone is a steroid compound derived from the estrane progestins. This compound strongly binds to the progesterone and glucocorticoid receptors, and to a lesser extent to the androgen receptor. As a result, this drug has a potent antiprogesterone, antiglucocorticoid and weak antiandrogen actions. Its main use as an abortifacient is due to the block of progesterone action which increases the uterine contractility, sensitizes the myometrium to prostaglandins, and elicits cervical maturing. This book discusses mifepristone on a vascular level, and provides the advantages and disadvantages of antiglucocorticoid and antiprogesterone activity of mifepristone. It also discusses the beneficial effects that this anitprogestin has in breast cancer.
Ariana Moore
Mifepristone [PDF ebook]
Pharmacology, Medical Uses and Potential Side Effects
Mifepristone [PDF ebook]
Pharmacology, Medical Uses and Potential Side Effects
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Formato PDF ● Pagine 102 ● ISBN 9781631179921 ● Editore Ariana Moore ● Casa editrice Nova Science Publishers ● Pubblicato 2014 ● Scaricabile 3 volte ● Moneta EUR ● ID 7224479 ● Protezione dalla copia Adobe DRM
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