Diabetes and Kidney Disease reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are covered, as well as an overview to the novel approaches being designed by leading researchers in the field.
A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.
Tabella dei contenuti
Background-History Part I: Natural Course, Pathogenesis, Morphology and Genetics 1. Diabetic Nephropathy—Scope of the problem (Epidemiology, US, Japan, Europe, Obesity (Metabolic Syndrome) Geriatrics 2. Natural Course (Stages/Evidence Based Discussion) 3. Pathogenesis: Biochemical and functional alterations involving the GBM and mesangium 4. Pathogenesis: Hemodynamic alterations/renin angiotensin system 5. Renal structural damage in type 1 and type 2 DM 6. Diabetes in children and adolescents 7. Genetic markers and predictors of DN Part II: Clinical Presentation and Associated Disorders 8. Screening and early diagnosis (E. Cohen – Milwaukee) 9. Differential diagnosis of proteinuria in DM (A. Reddi, NJ Med Sch) 10. Hypertension in DM 11. Cardiovascular Disease (L. Hamm, Tulane) 12. Lipid disorders 13. Eye complications in DN (Z. Karcioglu, U. Virginia) 14. Pregnancy and DN (K. Krane—Tulane) 15. Transplantation: Kidney, Kidney-Pancreas (R. Zhang) Part III: Treatment and Prognosis 16. Glycemic control 17. BP control in hypertensive diabetics with proteinuria 18. Early antihypertensive treatment in early stages of DN 19. Lifestyle modifications 20. Novel treatments (stem cells, islet cell transplants, gene transfer, etc.)
Circa l’autore
EDGAR V. LERMA, MD, FACP, FASN, FAHA, FASH, FNLA, FNKF Clinical Associate Professor of Medicine Section of Nephrology Department of Medicine University of Illinois at Chicago College of Medicine/ Associates in Nephrology, S.C.
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