This first comprehensive book to cover the expanding field of bioorganometallics represents the perfect starting point for beginners but also an excellent source of high quality information for experts in the field.
Edited by a pioneer in the field with an excellent standing within the community, this book begins with the history of bioorganometallics, before going on to cover pharmaceuticals, bioorganometallic chemistry and radiopharmaceuticals.
A must for bioinorganic chemists, the pharmaceutical industry, chemists working in organometallics and biochemists.
Tabella dei contenuti
A Novel Field of Research: Bioorganometallic Chemistry, Origins, and Founding Principles
Ruthenium Arene Anticancer Complexes
Organometallics Targeted to Specific Biological Sites: the Development of New Therapies
Radiopharmaceuticals
Conjugates of Peptides and PNA with Organometallic Complexes: Syntheses and Applications
Labeling of Proteins with Organometallic Complexes: Strategies and Applications
Organometallic Bioprobes
Organometallic Complexes as Tracers in Non-isotopic Immunoassay
Genosensors Based on Metal Complexes
Supramolecular Host Recognition Processes with Biological Compounds, Organometallic Pharmaceuticals, and Alkali-metal Ions as Guests
Structure and Mechanism of Metalloenzyme Active Sites
Synthetic Models for Bioorganometallic Reaction Centers
Circa l’autore
Gérard Jaouen he set up the CNRS URA (Associated Research Unit) N° 403, and the UMR
7576 in 1997, of which he is the director. He is now appointed as an exceptional class professor and has been elected as a member of the CNRS national Committee in 1991 and 1995.
Professor Jaouen is the author of 300 papers and 14 reviews, and holds 10 patents. His
achievements in bioorganometallic chemistry has been recognized by the French Academy of
Sciences in 1996, (J. Reynaud award) Moreover he has been elected to the prestigious and elitist ‘Institut Universitaire de France’ in 1997.