According to the World Health Organization, antimicrobial resistance is a major threat to global health because the number of alternative antibiotics is very limited. Antimicrobial resistance is a slow evolutionary process that has been accelerated by human activities in health, environment and agriculture sectors. Due to their wide application, antibiotics and their residues have been found in almost all food products and natural ecosystems. This book reviews the drivers, impact and mitigation of antimicrobial resistance, with focus on methods and targets.
Tabella dei contenuti
Preface.- Chapter 1 – Antimicrobial resistance paradigm and One-health approach.- Chapter 2 – Global surveillance programs on antimicrobial resistance.- Chapter 3 – Antimicrobial resistance, food systems and climate change.- Chapter 4 – In silico approaches for prioritizing drug targets in pathogens.- Chapter 5 – Molecular and systems biology approaches for analyzing drug-tolerant bacterial persister cells.- Chapter 6 – Role of gene editing tool CRISPR-Cas in the management of antimicrobial resistance.- Chapter 7 – Control of bacterial biofilms for mitigating antimicrobial resistance.- Chapter 8 – Intrusion of bacterial quorum-sensing for antimicrobial resistance mitigation: A pharmaceutical perspective.- Chapter 9 – Drug discovery for targeting drug resistant bacteria.
Circa l’autore
Dr. Harsh Panwar is currently Assistant Professor in Dairy Microbiology at the Department of Dairy Microbiology of Guru Angad Dev Veterinary and Animal Sciences University, India. His research interests include antimicrobial resistance and its mitigation in dairy and food. Dr. Panwar has published more than 36 articles in high impact journals. He is editorial board member for several international journals. He has been awarded Young Scientist Award 2019 by the Association of Microbiologists of India; Indo-Australian Career Boosting Gold Fellowship 2018-19 by Department of Biotechnology, Government of India; Best Teacher 2019 and Best Researcher 2018 Award by Guru Angad Dev Veterinary and Animal Sciences University; DST Inspire Fellowship by Department of Science and Technology, Government of India; Commonwealth Scholarships by Commonwealth Scholarship Commission, UK; and University Gold Medal by Kurukshetra University Kurukshetra.
Dr. Chetan Sharma isworking as a Research Advisor, Alpine Biomedicals Pvt. Ltd. Haryana, India. He has completed his M.Sc. and Ph.D. in Microbiology from Department of Microbiology, Kurukshetra University, Kurukshetra. He has published several research papers of international repute and serves as a reviewer for different journals. He has also edited and published one book by Nova Science Publishers, USA and two books from Springer Nature. His present research interest covers isolation of bioactive compounds from natural sources (plants), medical microbiology, antimicrobial resistance and probiotics.
Dr. Eric Lichtfouse is biogeochemist at the University of Aix-Marseille, France, and Visiting Professor at Xi’an Jioatong University. He has invented carbon-13 dating, a method allowing to measure the relative age of organic molecules occurring in different temporal pools of complex media. He is teaching scientific writing and communication, and has published the book Scientific Writing for Impact Factors, which includes a new tool – the Micro-Article – to identify the novelty of research results. He is founder and Chief Editor of scientific journals and series in environmental chemistry and agriculture. He has founded the European Association of Chemistry and the Environment. He got the Analytical Chemistry Prize by the French Chemical Society, the Grand Prize of the Universities of Nancy and Metz, and a Journal Citation Award by the Essential Indicators.
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