Hydrogels represent one of the cornerstones in tissue engineering and regenerative medicine, due to their biocompatibility and physiologically relevant properties. These inherent characteristics mean that they can be widely exploited as bioinks in 3D bioprinting for tissue engineering applications as well as injectable gels for cell therapy and drug delivery purposes. The research in these fields is booming and this book provides the reader with a terrific introduction to the burgeoning field of injectable hydrogel design, bioprinting and tissue engineering.
Edited by three leaders in the field, users of this book will learn about different classes of hydrogels, properties and synthesis strategies to produce bioinks. A section devoted to the key processing and design challenges at the hydrogel/3D bioprinting/tissue interface is also covered. The final section of the book closes with pertinent clinical applications.
Tightly edited, the reader will find this book to be a coherent resource to learn from. It will appeal to those working across biomaterials science, chemical and biomedical engineering, tissue engineering and regenerative medicine.
Tabella dei contenuti
Overview of Injectable Hydrogels for 3D Bioprinting and Tissue Regeneration;
Introduction to Hydrogel Synthesis and Crosslinking Methods for Developing Bioinks for 3D Bioprinting;
Characterizations of Hydrogels;
Naturally Occurring and Nature-derived Polymers as Injectable Hydrogels;
Self-assembling Hydrogels Based on Natural Building Blocks;
In Situ Forming Hydrogels;
Injectable Biopolymer Hydrogels for Regenerative Medicine;
Introduction to 3D Bioprinting of Injectable Hydrogels;
Hydrogel Processing Techniques and Vascular Tissue Engineering;
Rheological Aspects of Hydrogel Processing;
Interface (Cell, Gel, Surface) and Biocompatibility in Gel Processing;
Bioprinting Hydrogels and Tissue Engineering;
3D Bioprinting Hydrogel for Hard Tissue Regeneration;
3D-bioprinting for Engineering Complex Tissues and Vascularization;
Hydrogels–Blood Interactions;
Immuno-response and Hydrogels;
Application of Natural Hydrogels for Cell Therapy: Focus on Osteoarthritis;
Clinical Application and Regulation of Bioprinting Biomaterials Focusing on Hydrogels;
Status for Commercialization of FDA-approved Hydrogels and Their Intellectual Properties
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