This new volume in the Subcellular Biochemistry series will focus on the biochemistry and cellular biology of aging processes in human cells. The chapters will be written by experts in their respective fields and will focus on a number of the current key areas of research in subcellular aging research. Main topics for discussion are mitochondrial aging, protein homeostasis and aging and the genetic processes that are involved in aging. There will also be chapters that are dedicated to the study of the roles of a variety of vitamins and minerals on aging and a number of other external factors (microbiological, ROS, inflammation, nutrition). This book will provide the reader with a state of the art overview of the subcellular aging field. This book will be published in cooperation with a second volume that will discuss the translation of the cell biology of aging to a more clinical setting and it is hoped that the combination of these two volumes will bring a deeper understanding of the links between the cell and the body during aging.
Tabella dei contenuti
ROS, Mitochondrial Damage and ageing.- Protein homeostasis, protein aggregation and ageing.- Chronic inflammation and ageing.- Metabolic changes in ageing.- Gene expression, epigenetics and ageing.- Antioxidant Vitamins and ageing.- Vitamin B Complex, folic acid and ageing.- Vitamin D, Osteoporosis and ageing.- Cellular DNA damage and ageing.- Telomere Length, telomerase and ageing.- Signal transduction pathways in ageing.- Creatine, Creatine Kinase and ageing.- Cellular senescence.- Autophagy and ageing.- Extracellular matrix proteins and ageing.- Stem cells and ageing.- m TOR and Ageing.- Nutrition and ageing.- Microbiome and ageing.- Cholesterol and Ageing.
Circa l’autore
Prof. J. Robin Harris is an Honorary Professor of the University of Mainz, he has broad biomedical science and electron microscopical experience and is actively involved in scientific publishing.Dr. Viktor I. Korolchuk is a Reader in Molecular Cell Biology at Newcastle University and is actively involved in cellular autophagy studies.
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